Alcorn State vs Southern Miss Prediction, Picks, NCAAF Odds & Best Bets Today

College Football Betting Picks in Summary

• Southern Miss -19.5
• Southern Miss Over 434.5 Total Yards
• Under 51.5

Alcorn State travels to Southern Miss Saturday evening in a real mismatch — a -1400 moneyline with a team total more than double what the visitors are projected to score.

All college football odds come from FanDuel Sportsbook's college football betting odds and may change after this article is published.

College Football Predictions and Picks

Alcorn State at Southern Miss (Sat, 5:00 p.m. ET)

Southern Miss -19.5 (-108)

Southern Miss's own team total (35.5) is more than double Alcorn State's (15.5), a real, well-supported gap that lines up cleanly with the spread.

Southern Miss Over 434.5 Total Yards (-114)

Southern Miss's rushing attack alone is projected for 175.5 yards, meaning the passing game only needs to add another 259 or so to clear this number — a reasonable ask given the scale of the talent gap.

Under 51.5 (-110)

Adding the two individual team totals together (35.5 and 15.5) lands right at 51 — essentially this exact number — making the under a genuinely fair reflection of how the market expects the scoring to break down on both sides.