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4 Best Bets, Odds, Picks & Prediction for College Football Thursday Night Games October 22
Thursday Night College Football Best Bets in Summary
- Appalachian State -12.5
- Memphis -10.5
- Over 56.5 (James Madison vs Appalachian State)
- Liberty -8.5
Thursday's college football slate features three games, and the market has a clear hierarchy — Appalachian State is the biggest favorite of the night, while East Carolina at Memphis is the only game with a true road favorite covering the spread.
All college football odds come from FanDuel Sportsbook's college football betting odds and may change after this article is published.
Best Bets for Thursday Night College Football
James Madison at Appalachian State (7:00 p.m. ET)
Appalachian State -12.5 (-110)
Spread
The biggest spread of the night, a real sign the market expects Appalachian State to control this one at home from start to finish.
East Carolina at Memphis (7:30 p.m. ET)
Memphis -10.5 (-108)
Spread
A real, meaningful home favorite in this American Conference matchup, with the market giving Memphis a clear edge on both sides of the ball tonight.
Over 56.5 (-110)
Total
Comfortably the highest total of the night, a real sign the market expects Appalachian State's offense to pile up points even in a lopsided game.
Liberty at Kennesaw State (7:00 p.m. ET)
Liberty -8.5 (-110)
Spread
A real, meaningful road favorite to open the night, with the market giving Liberty a clear edge on both sides of the ball in this Conference USA matchup.
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Looking for the latest college football odds? Head over to FanDuel Sportsbook and check out all of the college football betting options.
You can also check out our How to Bet on College Football guide.
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The above author is a FanDuel employee and is not eligible to compete in public daily fantasy contests or place sports betting wagers on FanDuel. The advice provided by the author does not necessarily represent the views of FanDuel. Taking the author's advice will not guarantee a successful outcome. You should use your own judgment when participating in daily fantasy contests or placing sports wagers.
