49ers vs Jaguars Prediction, Odds, Picks, Best Bets for NFL Week 4

On Sunday in the NFL, the San Francisco 49ers are up against the Jacksonville Jaguars.

We've got you covered, in terms of the vital info about NFL betting lines, before you make your wager on FanDuel Sportsbook.

49ers vs Jaguars Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: 49ers win (55.9%)

49ers vs Jaguars Point Spread

The 49ers are 3.5-point favorites against the Jaguars. The 49ers are -102 to cover the spread, while the Jaguars are -120 to cover as a 3.5-point underdog.

49ers vs Jaguars Over/Under

49ers versus Jaguars on Sept. 28 has an over/under of 46.5 points, with the over -110 and the under -110.

49ers vs Jaguars Moneyline

Jacksonville is the underdog, +148 on the moneyline, while San Francisco is a -176 favorite at home.

49ers vs Jaguars Betting Trends

• San Francisco has posted two wins against the spread this year.
• The 49ers have had one game (out of three) hit the over this year.
• The Jaguars have two wins against the spread this season.
• Jacksonville has no wins ATS (0-1) as a 3.5-point underdog or more this year.
• The Jaguars have had one game (out of three) go over the total this year.

Check out even more in-depth 49ers vs. Jaguars analysis on FanDuel Research.

49ers vs Jaguars Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-176) | JAX: (+148)
• Spread: SF: -3.5 (-102) | JAX: +3.5 (-120)
• Total: 46.5 -- Over: (-110) | Under: (-110)

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