West Virginia vs Ohio Prediction, Odds, Picks, Best Bets for Week 2 2025

In college football action on Saturday, the West Virginia Mountaineers face the Ohio Bobcats.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the most important information about today's NCAA football betting odds.

West Virginia vs Ohio Odds & Spread

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: West Virginia: (-150) | Ohio: (+125)
• Spread: West Virginia: -3.5 (-102) | Ohio: +3.5 (-120)
• Total: 58.5 -- Over: (-110) | Under: (-110)

West Virginia vs Ohio Betting Trends

• West Virginia has posted one win against the spread this year.
• West Virginia has yet to lose ATS (1-0) as a 3.5-point favorite or greater this season.
• Ohio is unbeaten against the spread this year.
• Ohio has covered every time (1-0) as a 3.5-point or greater underdog this season.
• Ohio and its opponent have yet to finish under the total this year.

West Virginia vs Ohio Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Bobcats win (56.5%)

West Virginia vs Ohio Point Spread

Ohio is a 3.5-point underdog against West Virginia. Ohio is -120 to cover the spread, and West Virginia is -102.

West Virginia vs Ohio Over/Under

The over/under for the West Virginia versus Ohio matchup on Sept. 6 has been set at 58.5, with -110 odds on the over and -110 odds on the under.

West Virginia vs Ohio Moneyline

The West Virginia vs Ohio moneyline has West Virginia as a -150 favorite, while Ohio is a +125 underdog.

West Virginia vs. Ohio Points Insights

• The Mountaineers had an average implied point total of 31.9 last season, which is 0.9 points higher than their implied total in Saturday's game (31).
• The average implied point total last season for the Bobcats (29.6) is 1.6 more points than the team's implied total in this matchup (28).

West Virginia vs. Ohio Game Info

• Game day: Saturday, September 6, 2025
• Game time: 4 p.m. ET
• TV channel: ESPNU
• Location: Athens, Ohio
• Stadium: Frank Solich Field at Peden Stadium

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Check out even more in-depth West Virginia vs. Ohio analysis on FanDuel Research.