Vanderbilt vs LSU Prediction, Odds, Picks, Best Bets for Week 8 2025

In college football action on Saturday, the Vanderbilt Commodores face the LSU Tigers.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital information about today's NCAA football betting odds.

Vanderbilt vs LSU Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Vanderbilt: (-120) | LSU: (+102)
• Spread: Vanderbilt: -2.5 (-105) | LSU: +2.5 (-115)
• Total: 47.5 -- Over: (-110) | Under: (-110)

Vanderbilt vs LSU Betting Trends

• Vanderbilt has beaten the spread four times in six games.
• Vanderbilt has won twice ATS (2-1) as a 2.5-point or bigger favorite this season.
• Out of six Vanderbilt games so far this year, three have gone over the total.
• LSU has beaten the spread three times in six games.
• As a 2.5-point underdog or more, LSU has one win ATS (1-1) this year.
• One of LSU's six games has gone over the point total.

Vanderbilt vs LSU Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Commodores win (60.8%)

Vanderbilt vs LSU Point Spread

LSU is the underdog by 2.5 points against Vanderbilt. LSU is -105 to cover the spread, and Vanderbilt is -115.

Vanderbilt vs LSU Over/Under

The over/under for Vanderbilt-LSU on Oct. 18 is 47.5. The over is -110, and the under is -110.

Vanderbilt vs LSU Moneyline

The moneyline numbers for Vanderbilt vs. LSU reveal Vanderbilt as the favorite (-120) and LSU as the underdog (+102).

Vanderbilt vs. LSU Points Insights

Vanderbilt vs. LSU Game Info

• Game day: Saturday, October 18, 2025
• Game time: 12 p.m. ET
• TV channel: ABC
• Location: Nashville, Tennessee
• Stadium: FirstBank Stadium

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