Troy vs Southern Miss Prediction, Odds, Picks, Best Bets for Week 6 2026

The Troy Trojans will take on the Southern Miss Golden Eagles in college football action on Tuesday.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Troy vs Southern Miss Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Troy: (-365) | Southern Miss: (+285)
• Spread: Troy: -10.5 (-104) | Southern Miss: +10.5 (-118)
• Total: 49.5 -- Over: (-112) | Under: (-108)

Troy vs Southern Miss Betting Trends

• Troy has one win against the spread this season.
• Troy is winless ATS (0-2) as a 10.5-point favorite or greater this year.
• None of Troy's four games has gone over the point total in 2026.
• Southern Miss has won twice against the spread this year.
• As a 10.5-point underdog or greater, Southern Miss has one win ATS (1-1) this season.
• A pair of Southern Miss four games in 2026 have gone over the point total.

Troy vs Southern Miss Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Trojans win (70.7%)

Troy vs Southern Miss Point Spread

Troy is favored by 10.5 points (-104 to cover) in this matchup. Southern Miss, the underdog, is -118.

Troy vs Southern Miss Over/Under

The over/under for Troy-Southern Miss on Oct. 6 is 49.5. The over is -112, and the under is -108.

Troy vs Southern Miss Moneyline

The Troy vs Southern Miss moneyline has Troy as a -365 favorite, while Southern Miss is a +285 underdog.

Troy vs. Southern Miss Points Insights

Troy vs. Southern Miss Game Info

• Game day: Tuesday, October 6, 2026
• Game time: 8 p.m. ET
• TV channel: ESPN2
• Location: Troy, Alabama
• Stadium: Veterans Memorial Stadium (AL)

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Check out even more in-depth Troy vs. Southern Miss analysis on FanDuel Research.