Thunder vs. Grizzlies Prediction, Odds, Picks, Best Bets for Dec. 22

Thunder vs. Grizzlies Game Info

• Date: Monday, December 22, 2025
• Time: 9:30 p.m. ET
• Venue: Paycom Center -- Oklahoma City, Oklahoma
• Coverage: Peacock and FDSOK

The Oklahoma City Thunder (25-3) are heavy, 16.5-point favorites against the Memphis Grizzlies (13-15) on Monday, December 22, 2025 at 9:30 p.m. ET. The matchup airs on Peacock and FDSOK. The matchup has an over/under of 228.5 points.

Thunder vs. Grizzlies Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Thunder vs. Grizzlies Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Thunder win (76.8%)

Thunder vs. Grizzlies Betting Trends

• The Thunder have covered the spread 15 times this season (15-13-0).
• In the Grizzlies' 28 games this season, they have 13 wins against the spread.
• This season, 15 of the Thunder's games have gone over the point total.
• Grizzlies games this season have gone over the total in 10 of 28 opportunities (35.7%).
• Oklahoma City has done a better job covering the spread when playing at home (8-6-0) than it has in road tilts (7-7-0).
• The Thunder have exceeded the total in a higher percentage of games at home (57.1%) than away games (50%).
• Against the spread, Memphis has had better results away (7-7-0) than at home (6-8-0).
• Grizzlies games have gone above the over/under 42.9% of the time at home (six of 14), and 28.6% of the time away (four of 14).

Thunder Leaders

• Shai Gilgeous-Alexander averages 32.5 points, 4.7 boards and 6.4 assists, shooting 55.4% from the field and 43.2% from downtown, with 2.2 made treys per contest.
• Chet Holmgren is averaging 18.7 points, 7.8 boards and 1.6 assists. Defensively, he averages 0.6 steals and 1.5 blocked shots (sixth in league).
• Ajay Mitchell averages 14.1 points, 3.4 rebounds and 3.6 assists, shooting 46.8% from the field and 34.5% from beyond the arc, with 1.1 made 3-pointers per game.
• Isaiah Hartenstein is averaging 11.6 points, 10.6 boards and 3.1 assists.
• Cason Wallace averages 8 points, 3 rebounds and 2.4 assists, shooting 42.5% from the floor and 35.8% from downtown, with 1.4 made 3-pointers per contest.

Grizzlies Leaders

• Santi Aldama averages 13.8 points for the Grizzlies, plus 6.6 rebounds and 2.9 assists.
• Jaren Jackson Jr. averages 18 points, 5.3 boards and 2.1 assists. He is also making 47.8% of his shots from the floor and 35.8% from 3-point range, with 1.7 treys per contest.
• The Grizzlies receive 13.4 points per game from Cedric Coward, plus 6.2 rebounds and 2.8 assists.
• Jock Landale's numbers on the season are 10.8 points, 5.7 rebounds and 1.6 assists per contest. He is draining 51.5% of his shots from the field and 41.3% from 3-point range, with an average of 1.1 triples.
• Cam Spencer's numbers on the season are 12.3 points, 2.2 rebounds and 4.2 assists per contest. He is making 50.5% of his shots from the field and 50% from 3-point range (second in NBA), with an average of 2.6 triples.

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