Thunder vs. Cavaliers Prediction, Odds, Picks, Best Bets for Feb. 22

Thunder vs. Cavaliers Game Info

• Date: Sunday, February 22, 2026
• Time: 1 p.m. ET
• Venue: Paycom Center -- Oklahoma City, Oklahoma
• Coverage: ABC

The Cleveland Cavaliers (36-21) will attempt to continue a seven-game winning streak when they visit the Oklahoma City Thunder (43-14) on Sunday, February 22, 2026 at Paycom Center as only 2.5-point favorites. The contest airs at 1 p.m. ET on ABC. The matchup's point total is 224.5.

Thunder vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Thunder vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Thunder win (73.3%)

Thunder vs. Cavaliers Betting Trends

• The Cavaliers have covered the spread in a game 25 times this season (25-32-0).
• Against the spread, the Thunder are 28-28-1 this season.
• Cavaliers games have finished with a final combined score above the over/under 27 times this season.
• Thunder games this season have gone over the total in 31 of 57 opportunities (54.4%).
• Against the spread, Cleveland has performed worse when playing at home, covering 12 times in 30 home games, and 13 times in 27 road games.
• Looking at over/unders, the Cavaliers hit the over less consistently at home, as they've exceeded the total 12 times in 30 opportunities this season (40%). In road games, they have hit the over 15 times in 27 opportunities (55.6%).
• In 2025-26 against the spread, Oklahoma City has a lower winning percentage at home (.467, 14-16-0 record) than away (.519, 14-12-1).
• Thunder games have finished above the over/under less often at home (14 times out of 30) than on the road (17 of 27) this year.

Cavaliers Leaders

• Donovan Mitchell's numbers on the season are 28.8 points, 4.4 boards and 5.9 assists per game, shooting 48.6% from the floor and 37.6% from downtown, with an average of 3.6 made treys (second in league).
• James Harden's numbers on the season are 24.7 points, 4.8 boards and 8.2 assists per game, shooting 42.4% from the floor and 35.6% from beyond the arc, with an average of 3 made 3-pointers.
• Evan Mobley is averaging 17.7 points, 8.8 boards and 4 assists. Defensively, he averages 0.9 steals and 1.9 blocked shots (third in league).
• Jarrett Allen is averaging 14.9 points, 2 assists and 8.4 rebounds.
• Jaylon Tyson is averaging 13.6 points, 2.3 assists and 5.3 rebounds.

Thunder Leaders

• Chet Holmgren's numbers on the season are 17.4 points, 8.7 rebounds and 1.6 assists per contest. He is also draining 55.9% of his shots from the floor and 35.6% from beyond the arc, with an average of 1.3 triples.
• Cason Wallace's numbers on the season are 8.1 points, 3.1 boards and 2.3 assists per game. He is making 42.1% of his shots from the floor and 34% from beyond the arc, with an average of 1.3 triples.
• The Thunder get 10.6 points per game from Isaiah Hartenstein, plus 9.6 rebounds and 3.6 assists.
• Per game, Isaiah Joe gets the Thunder 10.5 points, 2.6 rebounds and 1.4 assists, plus 0.6 steals and 0.2 blocks.
• Aaron Wiggins averages 10.5 points, 3.5 boards and 1.8 assists. He is sinking 43.9% of his shots from the floor and 38.4% from 3-point range, with 1.8 treys per contest.

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