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Steelers vs Bills Prediction: NFL Preseason Predictions, Picks, Odds & Best Bets Tonight

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Steelers vs Bills Prediction: NFL Preseason Predictions, Picks, Odds & Best Bets Tonight

NFL Betting Picks in Summary

  • Under 34.5
  • Bills -3.5
  • 1st Half Under 17.5

Pittsburgh and Buffalo meet tonight in the final week of the 2026 preseason, when rosters are typically closest to their eventual 53-man cuts and most teams have already gotten what they need from their true starters.

All NFL preseason odds come from FanDuel Sportsbook's NFL betting odds and may change after this article is published.

NFL Predictions and Picks for Preseason Week 3

Pittsburgh Steelers at Buffalo Bills (Thu, 7 p.m. ET)

Under 34.5 (-110)

Total

Pittsburgh Steelers @ Buffalo Bills
Aug 27 7:00pm ETMore odds in Sportsbook

Final preseason week games are typically the least polished of the three, with roster-bubble players getting the bulk of the snaps and cutdowns just days away. That combination tends to produce more stalled drives than clean scoring.

Bills -3.5 (-104)

Spread

Buffalo Bills
Aug 27 7:00pm ETMore odds in Sportsbook

No player props were posted for this game, so this is a straightforward case of trusting the market — a modest home favorite number with nothing specific to argue against it.

1st Half Under 17.5 (-114)

1st Half Total

Pittsburgh Steelers @ Buffalo Bills
Aug 27 7:00pm ETMore odds in Sportsbook

Same logic in a tighter window — the earliest snaps in a Week 3 preseason game are especially likely to feature the deepest end of both rosters.


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The above author is a FanDuel employee and is not eligible to compete in public daily fantasy contests or place sports betting wagers on FanDuel. The advice provided by the author does not necessarily represent the views of FanDuel. Taking the author's advice will not guarantee a successful outcome. You should use your own judgment when participating in daily fantasy contests or placing sports wagers.

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