St. John's vs Villanova College Basketball Prediction, Odds, Picks, Best Bets for Feb. 28

The Villanova Wildcats (22-6, 13-4 Big East) will visit the St. John's Red Storm (22-6, 15-2 Big East) after winning three road games in a row.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

St. John's vs. Villanova Game Info and Odds

• Game day: Saturday, February 28, 2026
• Game time: 8 p.m. ET
• TV channel: FOX
• Location: New York City, New York
• Arena: Madison Square Garden

St. John's vs. Villanova Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: St. John's win (67.6%)

St. John's is a 7.5-point favorite against Villanova on Saturday and the total has been set at 147.5 points. Below are some betting trends and insights if you plan to place a wager on the outing.

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St. John's vs. Villanova: ATS Betting Stats and Trends

• St. John's has put together a 15-13-0 record against the spread this season.
• Villanova has covered 17 times in 28 chances against the spread this year.
• Villanova covers the spread when it is a 7.5-point underdog or more 66.7% of the time. That's more often than St. John's covers as a favorite of 7.5 or more (50%).
• Against the spread, the Red Storm have performed worse when playing at home, covering seven times in 15 home games, and six times in nine road games.
• The Wildcats' winning percentage against the spread at home is .467 (7-8-0). On the road, it is .700 (7-3-0).
• Against the spread, in conference play, St. John's is 10-7-0 this year.
• Villanova's Big East record against the spread is 9-8-0.

St. John's vs. Villanova: Moneyline Betting Stats

• St. John's has been victorious in 20, or 87%, of the 23 contests it has been chosen as moneyline favorites in this season.
• The Red Storm have a win-loss record of 16-1 when favored by -350 or better by oddsmakers this year.
• Villanova has won three of the eight games it was the underdog on the moneyline this season (37.5%).
• The Wildcats have played in three games as a moneyline underdog with odds of +275 or longer without claiming a victory.
• The moneyline set for this matchup implies St. John's has a 77.8% chance of coming away with a victory in the contest.

St. John's vs. Villanova Head-to-Head Comparison

• St. John's was 65th in the country in points scored (78.5 per game) and 27th in points conceded (65.8) last season.
• Last year, St. John's was eighth-best in the nation in rebounds (36.9 per game) and 182nd in rebounds conceded (31.2).
• Last season St. John's was ranked 53rd in the nation in assists with 15.7 per game.
• Last season, St. John's was 98th in the nation in turnovers committed (10.3 per game) and 17th-best in turnovers forced (14.2).
• Last year Villanova averaged 74.0 points per game (167th-ranked in college basketball) and gave up 68.2 points per contest (60th-ranked).
• With 27.7 rebounds allowed per game, Villanova was 17th-best in college basketball. It ranked 239th in college basketball by averaging 30.9 rebounds per contest.
• Villanova delivered 12.4 dimes per game, which ranked them 268th in the country.
• Villanova forced 9.6 turnovers per game last year (331st-ranked in college basketball), but it averaged only 9.1 turnovers per contest (12th-best).

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