SMU vs Wake Forest Prediction, Odds, Picks, Best Bets for Week 9 2025

The SMU Mustangs are among the college football teams busy on Saturday, versus the Wake Forest Demon Deacons.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

SMU vs Wake Forest Odds & Spread

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SMU: (-158) | Wake Forest: (+134)
• Spread: SMU: -3.5 (-102) | Wake Forest: +3.5 (-120)
• Total: 53.5 -- Over: (-110) | Under: (-110)

SMU vs Wake Forest Betting Trends

• SMU has two wins against the spread this season.
• SMU has won once ATS (1-2) as a 3.5-point or higher favorite this year.
• Two of six SMU games have hit the over this season.
• Against the spread, Wake Forest is 4-2-0 this year.
• Wake Forest has two wins ATS (2-1) as a 3.5-point underdog or more this season.
• There have been four Wake Forest games (out of six) that hit the over this year.

SMU vs Wake Forest Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Mustangs win (52.7%)

SMU vs Wake Forest Point Spread

Wake Forest is a 3.5-point underdog against SMU. Wake Forest is -120 to cover the spread, and SMU is -102.

SMU vs Wake Forest Over/Under

The over/under for the SMU versus Wake Forest game on Oct. 25 has been set at 53.5, with -110 odds on the over and -110 odds on the under.

SMU vs Wake Forest Moneyline

The moneyline numbers for SMU vs. Wake Forest reveal SMU as the favorite (-158) and Wake Forest as the underdog (+134).

SMU vs. Wake Forest Points Insights

SMU vs. Wake Forest Game Info

• Game day: Saturday, October 25, 2025
• Game time: 12 p.m. ET
• TV channel: The CW
• Location: Winston-Salem, North Carolina
• Stadium: Allegacy Federal Credit Union Stadium

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Check out even more in-depth SMU vs. Wake Forest analysis on FanDuel Research.