Pistons vs. Cavaliers Prediction, Odds, Picks, Best Bets for Feb. 27

Pistons vs. Cavaliers Game Info

• Date: Friday, February 27, 2026
• Time: 7 p.m. ET
• Venue: Little Caesars Arena -- Detroit, Michigan
• Coverage: ESPN, FDSDET, and FDSOH

Cade Cunningham and the Detroit Pistons (43-14) are 7-point favorites against Donovan Mitchell and the Cleveland Cavaliers (37-23) Friday, February 27, 2026 at Little Caesars Arena. The game starts at 7 p.m. ET on ESPN, FDSDET, and FDSOH. The over/under in the matchup is 225.5.

Pistons vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Pistons vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Pistons win (66.7%)

Pistons vs. Cavaliers Betting Trends

• The Pistons have covered the spread 31 times over 57 games with a set spread.
• The Cavaliers are 26-34-0 against the spread this season.
• Pistons games have gone over the total 26 times out of 60 chances this season.
• Cavaliers games this year have hit the over on 29 of 60 set point totals (48.3%).
• When playing at home, Detroit has a worse record against the spread (15-15-0) compared to its ATS record on the road (16-10-1).
• Looking at over/unders, the Pistons hit the over less consistently when playing at home, as they've exceeded the total 13 times in 30 opportunities this season (43.3%). In road games, they have hit the over 13 times in 27 opportunities (48.1%).
• Cleveland has performed better against the spread on the road (13-16-0) than at home (13-18-0) this year.
• Looking at the over/under, Cavaliers games have gone over less often at home (12 of 31, 38.7%) than on the road (17 of 29, 58.6%).

Pistons Leaders

• Cunningham averages 25.4 points, 5.7 boards and 9.8 assists, shooting 45.9% from the floor and 33.9% from beyond the arc, with 2 made treys per game.
• Jalen Duren is averaging 18.2 points, 10.6 rebounds and 1.7 assists. Defensively, he averages 0.9 steals and 0.7 blocked shots.
• Ausar Thompson is averaging 10.2 points, 2.9 assists and 5.8 rebounds.
• Duncan Robinson's numbers on the season are 12.4 points, 2.7 boards and 1.9 assists per game, shooting 43.7% from the field and 40% from beyond the arc, with an average of 3 made 3-pointers.
• Tobias Harris is averaging 13 points, 2.3 assists and 5.2 boards.

Cavaliers Leaders

• Mitchell averages 28.5 points, 4.5 boards and 5.8 assists. He is also draining 48.3% of his shots from the floor and 36.9% from 3-point range, with 3.5 triples per contest (second in NBA).
• James Harden's numbers on the season are 24.5 points, 4.8 boards and 8.1 assists per game. He is sinking 42.7% of his shots from the floor and 36% from beyond the arc, with an average of 3 triples.
• The Cavaliers receive 17.5 points per game from Evan Mobley, plus 8.6 rebounds and 3.9 assists.
• Jarrett Allen averages 15.1 points, 8.6 boards and 1.9 assists. He is sinking 63.3% of his shots from the field (seventh in NBA).
• The Cavaliers get 13.5 points per game from Jaylon Tyson, plus 5.4 rebounds and 2.2 assists.

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