Pistons vs. Cavaliers Prediction, Odds, Picks, Best Bets for Oct. 27

Pistons vs. Cavaliers Game Info

• Date: Monday, October 27, 2025
• Time: 7 p.m. ET
• Venue: Little Caesars Arena -- Detroit, Michigan
• Coverage: Peacock

The Cleveland Cavaliers (2-1) visit the Detroit Pistons (2-1) in a matchup of Central Division teams at Little Caesars Arena, beginning at 7 p.m. ET on Monday, October 27, 2025. The Cavaliers are 2.5-point favorites in the game, the first matchup between the squads this season. The over/under for the matchup is set at 231.5.

Pistons vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Pistons vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (51.2%)

Pistons vs. Cavaliers Betting Trends

• The Cavaliers won 47 games against the spread last season, while failing to cover or pushing 35 times.
• As 2.5-point underdogs or greater, the Pistons went 20-14-4 against the spread last year.
• Cavaliers games went over the point total 50 out of 82 times last season.
• In 82 Pistons games last season, 42 of them hit the over.
• Cleveland owned a worse record against the spread in home games (23-17-1) than it did in road games (24-16-1) last season.
• Detroit's winning percentage against the spread at home was .463 (19-20-2) last year. Away, it was .561 (23-16-2).

Cavaliers Leaders

• Donovan Mitchell put up 24 points, 4.5 boards and 5 assists last season. He also sank 44.3% of his shots from the floor and 36.8% from beyond the arc, with 3.3 triples per game (eighth in NBA).
• Evan Mobley recorded 18.5 points, 9.3 rebounds and 3.2 assists per game last season. He also posted 0.9 steals and 1.6 blocks (fourth in NBA).
• Darius Garland recorded 20.6 points, 2.9 rebounds and 6.7 assists per game, plus 1.2 steals and 0.1 blocks.
• Jarrett Allen averaged 13.5 points, 9.7 rebounds and 1.9 assists. He sank 70.6% of his shots from the floor (first in NBA).
• De'Andre Hunter's numbers last season were 17 points, 4 rebounds and 1.4 assists per game. He made 47% of his shots from the floor and 40.5% from 3-point range, with an average of 2.5 treys.

Pistons Leaders

• Cade Cunningham put up 26.1 points, 6.1 rebounds and 9.1 assists last season, shooting 46.9% from the field and 35.6% from downtown, with 2.1 made treys per contest.
• Jalen Duren collected 11.8 points last season, plus 2.7 assists and 10.3 rebounds.
• Tobias Harris put up 13.7 points, 2.2 assists and 5.9 rebounds.
• Caris LeVert put up 12.1 points, 3.4 assists and 3.2 boards.
• Ausar Thompson's numbers last season were 10.1 points, 5.1 boards and 2.3 assists per contest, shooting 53.5% from the floor.

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