Phillies vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for April 26

Odds updated as of 4:19 p.m.
The Philadelphia Phillies versus the Chicago Cubs is on the MLB schedule for Saturday.
All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.
Phillies vs Cubs Game Info
- Philadelphia Phillies (13-13) vs. Chicago Cubs (17-10)
- Date: Saturday, April 26, 2025
- Time: 4:05 p.m. ET
- Venue: Wrigley Field -- Chicago, Illinois
- Coverage: FOX
Phillies vs Cubs Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: PHI: (-116) | CHC: (-102)
- Spread: PHI: -1.5 (+150) | CHC: +1.5 (-182)
- Total: 7 -- Over: (-102) | Under: (-120)
Phillies vs Cubs Probable Starting Pitchers
Probable Pitchers: Jesús Luzardo (Phillies) - 2-0, 2.08 ERA vs Ben Brown (Cubs) - 2-1, 4.57 ERA
This contest's pitching matchup is set, as the Phillies will send Jesus Luzardo (2-0) to the mound, while Ben Brown (2-1) will take the ball for the Cubs. Luzardo and his team are 3-2-0 ATS this season when he starts. Luzardo's team has won 66.7% of his starts when they are favored on the moneyline (2-1). When Brown starts, the Cubs are 3-1-0 against the spread. The Cubs were named the moneyline underdog for one Brown start this season -- they won.
Phillies vs Cubs Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (51.5%)
Phillies vs Cubs Moneyline
- Looking at the moneyline for Phillies-Cubs, Philadelphia is the favorite at -116, and Chicago is -102 playing at home.
Phillies vs Cubs Spread
- The Cubs are hosting the Phillies, and are +1.5 on the runline. The Cubs are +150 to cover the spread, and the Phillies are -182.
Phillies vs Cubs Over/Under
- Phillies versus Cubs on April 26 has an over/under of 7 runs, with the odds on the over -102 and the under set at -120.
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Phillies vs Cubs Betting Trends
- The Phillies have come away with 10 wins in the 19 contests they have been listed as the favorites in this season.
- This season Philadelphia has come away with a win 10 times in 18 chances when named as a favorite of at least -116 on the moneyline.
- The Phillies and their opponents have gone over in 12 of their 25 games with a total set by sportsbooks this season.
- The Phillies are 13-12-0 against the spread in their 25 games with a line set by sportsbooks this season.
- The Cubs are 7-6 in games they were listed as the moneyline underdog (winning 53.8% of those games).
- When playing as a moneyline underdog with odds of -102 or longer, Chicago has a 6-5 record (winning 54.5% of its games).
- The Cubs have combined with opponents to go over the total 17 times this season for a 17-7-1 record against the over/under.
- The Cubs have covered 56% of their games this season, going 14-11-0 against the spread.
Phillies Player Leaders
- Kyle Schwarber leads Philadelphia with 23 hits and an OBP of .405 this season. He has a .250 batting average and a slugging percentage of .511.
- Among qualified hitters in the majors, he ranks 77th in batting average, 13th in on-base percentage, and 27th in slugging.
- Bryce Harper has four doubles, five home runs and 21 walks. He's batting .240 and slugging .438 with an on-base percentage of .376.
- Among qualified hitters, he is 90th in batting average, 31st in on-base percentage and 57th in slugging percentage.
- Bryson Stott has 25 hits this season and has a slash line of .284/.354/.420.
- Nicholas Alexander Castellanos leads Philadelphia with a slugging percentage of .447, fueled by 10 extra-base hits.
- Castellanos has hit safely in two games in a row. In his last five games he is hitting .158 with a double, two walks and two RBI.
Cubs Player Leaders
- Kyle Tucker has a team-best OBP (.414) and slugging percentage (.617), and paces the Cubs in hits (33, while batting .308).
- Including all qualifying hitters in the big leagues, his batting average places him 21st, his on-base percentage is seventh, and he is sixth in slugging.
- Pete Crow-Armstrong has nine doubles, a triple, five home runs and six walks while hitting .295. He's slugging .543 with an on-base percentage of .339.
- His batting average is 28th among all qualified players, his on-base percentage is 68th, and he is 17th in slugging.
- Carson Kelly has a double, a triple, six home runs and 15 walks while batting .341.
- Ian Happ has seven doubles, two home runs and 15 walks while batting .274.
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