Phillies vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 9

Odds updated as of 1:12 a.m.

The Philadelphia Phillies versus the Houston Astros is on the MLB schedule for Wednesday.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Phillies vs Astros Game Info

• Philadelphia Phillies (81-64) vs. Houston Astros (74-71)
• Date: Wednesday, September 9, 2026
• Time: 6:40 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and SCHN

Phillies vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-154) | HOU: (+130)
• Spread: PHI: -1.5 (+126) | HOU: +1.5 (-152)
• Total: 8.5 -- Over: (+106) | Under: (-130)

Phillies vs Astros Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 16-5, 2.58 ERA vs Hunter Brown (Astros) - 5-3, 3.31 ERA

The Phillies will call on Cristopher Sanchez (16-5) versus the Astros and Hunter Brown (5-3). Sanchez and his team have a record of 17-12-0 against the spread when he starts. Sanchez's team is 21-8 this season when he starts and they are the moneyline favorite. The Astros are 8-8-0 against the spread when Brown starts. The Astros were named the moneyline underdog for two Brown starts this season -- they split the games.

Phillies vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (59%)

Phillies vs Astros Moneyline

• The Phillies vs Astros moneyline has Philadelphia as a -154 favorite, while Houston is a +130 underdog on the road.

Phillies vs Astros Spread

• The Astros are at +1.5 on the runline against the Phillies. The Astros are -152 to cover the spread, and the Phillies are +126.

Phillies vs Astros Over/Under

• A combined run total of 8.5 has been set for Phillies-Astros on Sept. 9, with the over at +106 and the under at -130.

Bet on Philadelphia Phillies vs. Houston Astros on FanDuel today!

Phillies vs Astros Betting Trends

• The Phillies have come away with 70 wins in the 108 contests they have been listed as the favorites in this season.
• Philadelphia has a record of 45-14 in contests when bookmakers favor them by -154 or more on the moneyline.
• The Phillies and their opponents have hit the over in 66 of their 141 games with a total set by oddsmakers this season.
• In 141 games with a line this season, the Phillies have a mark of 59-82-0 against the spread.
• The Astros have been the underdog on the moneyline 75 total times this season. They've finished 39-36 in those games.
• In games it has played as a moneyline underdog with odds of +130 or longer, Houston has a 5-8 record (winning just 38.5% of its games).
• The Astros have played in 145 games with an over/under set, and have combined with opponents to go over the total 73 times (73-65-7).
• The Astros have gone 73-72-0 ATS this season.

Phillies Player Leaders

• Bryce Harper has 138 hits this season and a team-best OBP of .388. He has a .271 batting average and a slugging percentage of .497.
• Among the qualified hitters in MLB, his batting average ranks 40th, his on-base percentage ranks fifth, and he is 15th in slugging.
• Luis Arraez has an OPS of .776, fueled by an OBP of .348 and a team-best slugging percentage of .428 this season. He's batting .316.
• His batting average ranks first among qualified players, his on-base percentage 42nd, and his slugging percentage 65th.
• Kyle Schwarber has 126 hits and is batting .242 this season.
• Schwarber enters this game with four games in a row with at least one hit. In his last five games he is hitting .316 with three home runs, three walks and five RBIs.
• Bryson Stott has 10 home runs, 61 RBI and a batting average of .252 this season.

Astros Player Leaders

• Yordan Alvarez has 160 hits with a .428 on-base percentage and a .593 slugging percentage, all club-bests for the Astros. He's batting .311.
• Including all qualified hitters, he ranks second in batting average, while his on-base percentage is first and he is first in slugging.
• Isaac Paredes is batting .258 with 25 doubles, a triple, 18 home runs and 63 walks. He's slugging .420 with an on-base percentage of .359.
• Including all qualified hitters, his batting average places him 65th, his on-base percentage ranks 31st, and he is 71st in slugging.
• Christian Walker is batting .230 with 25 doubles, a triple, 25 home runs and 46 walks.
• Jose Altuve is batting .244 with 20 doubles, two triples, 15 home runs and 39 walks.

Phillies vs Astros Head to Head

• 9/8/2026: 6-5 HOU (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/26/2025: 2-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/25/2025: 2-0 HOU (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/24/2025: 1-0 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/28/2024: 10-0 HOU (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/27/2024: 5-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/26/2024: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 4/30/2023: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/29/2023: 6-1 PHI (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/28/2023: 3-1 PHI (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)

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