Phillies vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 9

Odds updated as of 6:12 p.m.

The Philadelphia Phillies will take on the Houston Astros in MLB action on Wednesday.

We've got you covered, in terms of the vital information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Phillies vs Astros Game Info

• Philadelphia Phillies (81-64) vs. Houston Astros (74-71)
• Date: Wednesday, September 9, 2026
• Time: 6:40 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and SCHN

Phillies vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-154) | HOU: (+130)
• Spread: PHI: -1.5 (+138) | HOU: +1.5 (-166)
• Total: 8.5 -- Over: (+108) | Under: (-132)

Phillies vs Astros Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 16-5, 2.58 ERA vs Hunter Brown (Astros) - 5-3, 3.31 ERA

The Phillies will give the nod to Cristopher Sanchez (16-5, 2.58 ERA), who is eyeing win No. 17 on the season, and the Astros will counter with Hunter Brown (5-3, 3.31 ERA). Sanchez and his team are 17-12-0 ATS this season when he starts. Sanchez's team is 21-8 this season when he starts and they are the moneyline favorite. The Astros have gone 8-8-0 against the spread when Brown starts. The Astros were named the moneyline underdog for two Brown starts this season -- they split the games.

Phillies vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (59.4%)

Phillies vs Astros Moneyline

• Looking at the moneyline for Astros-Phillies, Houston is the underdog at +130, and Philadelphia is -154 playing at home.

Phillies vs Astros Spread

• The Astros are at +1.5 on the runline against the Phillies. The Astros are -166 to cover the spread, and the Phillies are +138.

Phillies vs Astros Over/Under

• The Phillies-Astros contest on Sept. 9 has been given an over/under of 8.5 runs. The over is set at +108 and the under at -132.

Bet on Philadelphia Phillies vs. Houston Astros on FanDuel today!

Phillies vs Astros Betting Trends

• The Phillies have come away with 70 wins in the 108 contests they have been listed as the favorites in this season.
• This season Philadelphia has been victorious 45 times in 59 chances when named as a favorite of at least -154 on the moneyline.
• The Phillies and their opponents have hit the over in 66 of their 141 games with a total set by oddsmakers this season.
• In 141 games with a line this season, the Phillies have a mark of 59-82-0 against the spread.
• The Astros have been the moneyline underdog 75 total times this season. They've gone 39-36 in those games.
• Houston has a 5-8 record (winning only 38.5% of its games) when it has played as a moneyline underdog of +130 or longer.
• The Astros have played in 145 games with a set over/under, and have combined with their opponents to go over the total 73 times (73-65-7).
• The Astros are 73-72-0 against the spread this season.

Phillies Player Leaders

• Bryce Harper has 138 hits this season and a team-best OBP of .388. He has a .271 batting average and a slugging percentage of .497.
• Among qualified hitters in baseball, he is 40th in batting average, fifth in on-base percentage, and 15th in slugging.
• Luis Arraez has an OPS of .776, fueled by an OBP of .348 and a team-best slugging percentage of .428 this season. He's batting .316.
• Among qualified hitters, his batting average ranks him first, his on-base percentage 43rd, and his slugging percentage 65th.
• Kyle Schwarber has 126 hits and is batting .242 this season.
• Schwarber brings a four-game hitting streak into this game. During his last five outings he is hitting .316 with three home runs, three walks and five RBIs.
• Bryson Stott is batting .252 with a .327 OBP and 61 RBI for Philadelphia this season.

Astros Player Leaders

• Yordan Alvarez has accumulated 160 hits with a .428 on-base percentage and a .593 slugging percentage, all club-bests for the Astros. He's batting .311.
• Including all the qualified players in MLB, his batting average ranks second, his on-base percentage is first, and he is first in slugging.
• Isaac Paredes is batting .258 with 25 doubles, a triple, 18 home runs and 63 walks. He's slugging .420 with an on-base percentage of .359.
• His batting average ranks 64th among all qualified players, his on-base percentage is 31st, and he is 70th in slugging.
• Christian Walker is batting .230 with 25 doubles, a triple, 25 home runs and 46 walks.
• Jose Altuve has 20 doubles, two triples, 15 home runs and 39 walks while hitting .244.

Phillies vs Astros Head to Head

• 9/8/2026: 6-5 HOU (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/26/2025: 2-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/25/2025: 2-0 HOU (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/24/2025: 1-0 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/28/2024: 10-0 HOU (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/27/2024: 5-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/26/2024: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 4/30/2023: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/29/2023: 6-1 PHI (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/28/2023: 3-1 PHI (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)

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