Patrick Mahomes Fantasy Football Week 6: Stats and Projections vs. Lions

Quarterback Patrick Mahomes is looking at a matchup versus the 11th-ranked pass defense in the NFL (206.6 yards allowed per game) in Week 6, when his Kansas City Chiefs take on the Detroit Lions, Sunday at 8:20 p.m. ET.

With Mahomes' next game against the Lions, should you think about him for your DFS lineup? Scroll down for more stats and information.

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Patrick Mahomes Week 6 Fantasy Football Projection

• Matchup: Kansas City Chiefs vs. Detroit Lions
• Game Date: October 12, 2025
• Game Time: 8:20 p.m.
• Projected Fantasy Points: 19.3
• Projected Passing Yards: 237.98
• Projected Passing TDs: 1.92
• Projected Rushing Yards: 23.34
• Projected Rushing TDs: 0.22

Projections provided by numberFire

Mahomes Fantasy Performance

• With 115.3 fantasy points in 2025 (23.1 per game), Mahomes is the seventh-ranked player at the QB position and eighth among all players.
• In his last three games, Mahomes has put up 67.2 fantasy points (22.4 per game), connecting on 76-of-115 passes for 812 yards, six touchdowns, and one interception. He's added 67 rushing yards on 15 carries with one touchdown on the ground.
• The peak of Mahomes' fantasy season came against the Baltimore Ravens in Week 4, when he racked up 27.3 fantasy points with 270 passing yards, four TDs, and zero picks. With his legs, he added five rushing yards on four carries (1.3 YPC) .
• From a fantasy perspective, Patrick Mahomes stumbled to his worst performance of the season in Week 3 against the New York Giants, throwing for 224 yards and one touchdown with zero interceptions (13.2 fantasy points).

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Lions Defensive Performance

• Not a single QB has recorded more than 300 yards passing in a game versus Detroit this season.
• The Lions have given up at least one passing TD to four opposing QBs this year.
• A total of four players have thrown for at least two touchdowns versus Detroit this season.
• The Lions have allowed two players to pass for three or more TDs in a game this season.
• Detroit has given up more than 100 yards receiving to two players this year.
• The Lions have allowed a TD reception by seven players this season.
• Detroit has given up at least two receiving TDs to three players this season.
• No player has collected over 100 yards on the ground in a game against the Lions this year.
• Detroit has allowed four players to score at least one rushing touchdown versus them this season.
• No player has rushed for more than one touchdown versus the Lions this year.

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