Panthers vs Sabres NHL Prediction, Odds, Picks, Best Bets for Jan. 12

The Monday slate in the NHL includes a matchup between the Buffalo Sabres and the Florida Panthers.

We've got you covered, in terms of the vital information about NHL betting lines, before you make your wager on FanDuel Sportsbook.

Sabres vs Panthers Game Info

• Buffalo Sabres (24-15-4) vs. Florida Panthers (23-18-3)
• Date: Monday, January 12, 2026
• Time: 7 p.m. ET
• Venue: KeyBank Center -- Buffalo, New York
• Coverage: ESPN+

Sabres vs Panthers Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Sabres vs Panthers Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Sabres win (52.3%)

Sabres vs Panthers Puck Line

• The Sabres are favored by 1.5 goals (+198 to cover). Florida, the underdog, is -250.

Sabres vs Panthers Over/Under

• A combined goal total of 6.5 has been set for Sabres-Panthers on Jan. 12, with the over at +106 and the under at -130.

Sabres vs Panthers Moneyline

• Florida is the underdog, +102 on the moneyline, while Buffalo is a -122 favorite at home.

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