Panthers vs Penguins NHL Prediction, Odds, Picks, Best Bets for Oct. 23

The NHL's Thursday slate includes the Florida Panthers taking on the Pittsburgh Penguins.

We've got you covered, in terms of the vital information about NHL betting lines, before you make your wager on FanDuel Sportsbook.

Panthers vs Penguins Game Info

• Florida Panthers (4-4) vs. Pittsburgh Penguins (5-2)
• Date: Thursday, October 23, 2025
• Time: 7 p.m. ET
• Venue: Amerant Bank Arena -- Sunrise, Florida
• Coverage: ESPN+

Panthers vs Penguins Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Panthers vs Penguins Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Panthers win (67.7%)

Panthers vs Penguins Puck Line

• The Penguins are 1.5-goal underdogs against the Panthers. The Penguins are -154 to cover the spread, and the Panthers are +126.

Panthers vs Penguins Over/Under

• The over/under for Panthers-Penguins on Oct. 23 is 5.5. The over is -140, and the under is +114.

Panthers vs Penguins Moneyline

• Pittsburgh is a +164 underdog on the moneyline, while Florida is a -200 favorite at home.

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