Padres vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for May 3

Odds updated as of 3:11 p.m.

The Pittsburgh Pirates are among the MLB squads playing on Saturday, versus the San Diego Padres.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Pirates vs Padres Game Info

• Pittsburgh Pirates (12-21) vs. San Diego Padres (20-11)
• Date: Saturday, May 3, 2025
• Time: 4:05 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and SDPA

Pirates vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-120) | SD: (+102)
• Spread: PIT: -1.5 (+158) | SD: +1.5 (-192)
• Total: 9 -- Over: (-120) | Under: (-102)

Pirates vs Padres Probable Starting Pitchers

Probable Pitchers: Bailey Falter (Pirates) - 1-3, 5.93 ERA vs Randy Vasquez (Padres) - 1-3, 4.28 ERA

The probable pitchers are Bailey Falter (1-3) for the Pirates and Randy Vasquez (1-3) for the Padres. Falter and his team are 2-4-0 ATS this season when he starts. Falter's team is 1-1 this season when he starts and they're favored on the moneyline. The Padres are 3-3-0 against the spread when Vasquez starts. The Padres have been the moneyline underdog in six of Vasquez's starts this season, and they went 2-4 in those matchups.

Pirates vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (59.9%)

Pirates vs Padres Moneyline

• Pittsburgh is a -120 favorite on the moneyline, while San Diego is a +102 underdog on the road.

Pirates vs Padres Spread

• The Padres are at +1.5 on the runline against the Pirates. The Padres are -192 to cover the spread, and the Pirates are +158.

Pirates vs Padres Over/Under

• An over/under of 9 has been set for Pirates-Padres on May 3, with the over being -120 and the under -102.

Bet on Pittsburgh Pirates vs. San Diego Padres on FanDuel today!

Pirates vs Padres Betting Trends

• The Pirates have been victorious in five, or 41.7%, of the 12 contests they have been chosen as favorites in this season.
• This year Pittsburgh has won three of nine games when listed as at least -120 on the moneyline.
• The Pirates and their opponents have gone over in 16 of their 33 games with a total set by sportsbooks this season.
• The Pirates are 12-21-0 against the spread in their 33 games with a line set by sportsbooks this season.
• The Padres have won 50% of the games this season they were the underdog on the moneyline (7-7).
• San Diego has a record of 5-5 when playing as a moneyline underdog with odds of +102 or longer (50%).
• The Padres have played in 31 games with a set over/under, and have combined with their opponents to go over the total 13 times (13-17-1).
• The Padres have covered 58.1% of their games this season, going 18-13-0 ATS.

Pirates Player Leaders

• Oneil Cruz leads Pittsburgh in OBP (.364) and total hits (26) this season. He's batting .245 batting average while slugging .519.
• Among qualifying batters in MLB, he is 85th in batting average, 38th in on-base percentage, and 23rd in slugging.
• Andrew McCutchen is hitting .264 with six doubles, three home runs and 12 walks. He's slugging .429 with an on-base percentage of .356.
• His batting average is 65th among qualified players, his on-base percentage 47th, and his slugging percentage 65th.
• Bryan Reynolds has hit four homers with a team-high .377 SLG this season.
• Reynolds has logged a hit or more in three straight games. In his last five games he is batting .263 with a double, a home run, two walks and three RBI.
• Enmanuel Valdez is batting .216 with a .318 OBP and 12 RBI for Pittsburgh this season.

Padres Player Leaders

• Fernando Tatis Jr. has totaled 39 hits with a .419 on-base percentage and a .602 slugging percentage, all club-highs for the Padres. He's batting .345.
• He is third in batting average, fifth in on-base percentage and sixth in slugging percentage among all qualified hitters in MLB.
• Manny Machado is hitting .278 with 10 doubles, two home runs and 11 walks. He's slugging .417 with an on-base percentage of .339.
• Including all qualified hitters, his batting average puts him 41st, his on-base percentage ranks 64th, and he is 74th in slugging.
• Luis Arraez is batting .313 with four doubles, a triple, three home runs and five walks.
• Xander Bogaerts is hitting .243 with eight doubles, a home run and 14 walks.

Pirates vs Padres Head to Head

• 5/2/2025: 9-4 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/14/2024: 8-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/13/2024: 3-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 8/12/2024: 2-1 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/8/2024: 7-6 SD (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/7/2024: 9-8 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/6/2024: 6-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 7/26/2023: 3-2 PIT (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 7/25/2023: 5-1 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -290, Underdog Moneyline: +235)
• 7/24/2023: 8-4 PIT (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -275, Underdog Moneyline: +225)

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