Padres vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 19

Odds updated as of 8:11 p.m.

MLB action on Saturday includes the San Diego Padres facing the Miami Marlins.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Padres vs Marlins Game Info

• San Diego Padres (85-69) vs. Miami Marlins (76-78)
• Date: Saturday, September 19, 2026
• Time: 8:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and Marlins.TV

Padres vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-134) | MIA: (+116)
• Spread: SD: -1.5 (+162) | MIA: +1.5 (-196)
• Total: 7.5 -- Over: (-140) | Under: (+114)

Padres vs Marlins Probable Starting Pitchers

Probable Pitchers: Casey Mize (Padres) - 6-9, 3.69 ERA vs Eury Pérez (Marlins) - 7-11, 3.99 ERA

The Padres will call on Casey Mize (6-9) versus the Marlins and Eury Perez (7-11). Mize's team is 11-13-0 against the spread this season in his starts. Mize's team has a record of 8-6 this season when he starts and they are the favorite on the moneyline. The Marlins are 13-13-0 against the spread when Perez starts. The Marlins have been the moneyline underdog in 14 of Pérez's starts this season, and they went 6-8 in those matchups.

Padres vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (53.4%)

Padres vs Marlins Moneyline

• San Diego is a -134 favorite on the moneyline, while Miami is a +116 underdog on the road.

Padres vs Marlins Spread

• The Padres are 1.5-run home favorites on the runline against the Marlins. The Padres are +162 to cover, and the Marlins are -196.

Padres vs Marlins Over/Under

• The over/under for Padres-Marlins on Sept. 19 is 7.5. The over is -140, and the under is +114.

Bet on San Diego Padres vs. Miami Marlins on FanDuel today!

Padres vs Marlins Betting Trends

• The Padres have been favorites in 76 games this season and have come away with the win 46 times (60.5%) in those contests.
• This season San Diego has come away with a win 29 times in 42 chances when named as a favorite of at least -134 on the moneyline.
• The Padres and their opponents have gone over the total this season in 72 of their 154 opportunities.
• The Padres are 89-65-0 against the spread in their 154 games with a line set by sportsbooks this season.
• The Marlins have won 40.7% of the games this season they were the underdog on the moneyline (35-51).
• In games it has played as a moneyline underdog with odds of +116 or longer, Miami has an 18-25 record (winning 41.9% of its games).
• The Marlins have had an over/under set by oddsmakers 152 times, and have combined with opponents to go over the total in 77 of those games (77-73-2).
• The Marlins have a 78-74-0 record ATS this season (covering 51.3% of the time).

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego with 171 hits and an OBP of .355, plus a team-best slugging percentage of .461. He's batting .285.
• He ranks 16th in batting average, 37th in on-base percentage, and 37th in slugging among qualified batters in baseball.
• Tatis will look for his third straight game with a hit in this matchup. During his last five outings he is hitting .182 with a double, two home runs, two walks and four RBIs.
• Jackson Merrill has 25 doubles, five triples, 26 home runs and 39 walks. He's batting .256 and slugging .448 with an on-base percentage of .304.
• His batting average ranks 69th among qualified players, his on-base percentage 112th, and his slugging percentage 48th.
• Merrill enters this game looking to extend his nine-game hit streak. During his last 10 games he is batting .442 with two doubles, two triples, four home runs, a walk and 14 RBIs.
• Manny Machado has 122 hits this season and has a slash line of .219/.308/.409.
• Xander Bogaerts is batting .228 with a .326 OBP and 56 RBI for San Diego this season.
• Bogaerts has safely hit in two straight games. In his last five games he is batting .389 with two doubles, a triple, a home run, three walks and two RBIs.

Marlins Player Leaders

• Otto Lopez has a .441 slugging percentage, which leads the Marlins. He's batting .307 with an on-base percentage of .349.
• Including all qualifying hitters in the majors, he ranks fourth in batting average, 43rd in on-base percentage and 54th in slugging percentage.
• Xavier Edwards leads his team with a .361 OBP. He has a batting average of .282 while slugging .373.
• He is 20th in batting average, 28th in on-base percentage and 112th in slugging percentage in the majors.
• Javier Sanoja has 31 doubles, five triples, nine home runs and 25 walks while batting .294.
• Jakob Marsee has 19 doubles, six triples, 11 home runs and 75 walks while hitting .228.

Padres vs Marlins Head to Head

• 9/18/2026: 8-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 7/26/2026: 5-3 SD (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/25/2026: 7-2 SD (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/24/2026: 4-2 SD (Favorite: Marlins, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/23/2025: 3-2 MIA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/22/2025: 4-3 MIA (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/21/2025: 2-1 SD (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/28/2025: 10-8 MIA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/27/2025: 8-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/26/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)

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