Ohio vs Northern Illinois Prediction, Odds, Picks, Best Bets for Week 8 2025

In college football action on Saturday, the Ohio Bobcats play the Northern Illinois Huskies.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Ohio vs Northern Illinois Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Ohio: (-429) | Northern Illinois: (+340)
• Spread: Ohio: -11.5 (-105) | Northern Illinois: +11.5 (-115)
• Total: 42.5 -- Over: (-110) | Under: (-110)

Ohio vs Northern Illinois Betting Trends

• Ohio has four wins in six games against the spread this year.
• Ohio is winless ATS (0-2) as an 11.5-point favorite or greater this season.
• This season, three of Ohio's six games have hit the over.
• Northern Illinois has but one win versus the spread this season.
• As an 11.5-point underdog or more, Northern Illinois has one win ATS (1-1) this season.
• One Northern Illinois game (out of six) has hit the over this season.

Ohio vs Northern Illinois Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Bobcats win (72.7%)

Ohio vs Northern Illinois Point Spread

Ohio is favored by 11.5 points over Northern Illinois. Ohio is -105 to cover the spread, with Northern Illinois being -115.

Ohio vs Northern Illinois Over/Under

A total of 42.5 points has been set for the Ohio-Northern Illinois game on Oct. 18, with the over available at -110 and the under at -110.

Ohio vs Northern Illinois Moneyline

The Ohio vs Northern Illinois moneyline has Ohio as a -429 favorite, while Northern Illinois is a +340 underdog.

Ohio vs. Northern Illinois Points Insights

Ohio vs. Northern Illinois Game Info

• Game day: Saturday, October 18, 2025
• Game time: 3:30 p.m. ET
• TV channel: ESPN+
• Location: Athens, Ohio
• Stadium: Frank Solich Field at Peden Stadium

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Check out even more in-depth Ohio vs. Northern Illinois analysis on FanDuel Research.