North Carolina vs East Carolina College Basketball Prediction, Odds, Picks, Best Bets for Dec. 22

The North Carolina Tar Heels (11-1) will attempt to continue a five-game winning streak when they host the East Carolina Pirates (5-7) on December 22, 2025 at Dean E. Smith Center.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

North Carolina vs. East Carolina Game Info and Odds

• Game day: Monday, December 22, 2025
• Game time: 8 p.m. ET
• TV channel: ACC Network
• Location: Chapel Hill, North Carolina
• Arena: Dean E. Smith Center

North Carolina vs. East Carolina Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: North Carolina win (97.6%)

North Carolina is a 25.5-point favorite over East Carolina on Monday and the total is set at 145.5 points. Here's some betting trends and insights if you are planning on making a wager on the contest.

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North Carolina vs. East Carolina: ATS Betting Stats and Trends

• North Carolina is 7-5-0 ATS this season.
• East Carolina has covered three times in 11 games with a spread this year.
• The Tar Heels covered the spread in a higher percentage of their home games than away games last season. They covered seven times in 15 opportunities when playing at home, and they covered four times in 12 opportunities in road games.
• Last year, the Pirates were 7-9-0 at home against the spread (.438 winning percentage). On the road, they were 5-5-0 ATS (.500).

North Carolina vs. East Carolina: Moneyline Betting Stats

• North Carolina has been named as the moneyline favorite nine times this year and has yet to lose any of those games.
• The Tar Heels have not lost in three games this year when favored by -10000 or better on the moneyline.
• East Carolina has lost all four of the games it has been the underdog on the moneyline this season.
• The Pirates have not yet played as a moneyline underdog of +3000 or longer.
• Bookmakers have implied with the moneyline set for this matchup that North Carolina has a 99% chance of pulling out a win.

North Carolina vs. East Carolina Head-to-Head Comparison

• At 80.7 points scored per game and 74.7 points conceded last year, North Carolina was 29th in the country on offense and 261st defensively.
• Last season, North Carolina was 105th in the nation in rebounds (33.2 per game) and 182nd in rebounds allowed (31.2).
• North Carolina was 93rd in the country in assists (14.7 per game) last year.
• At 10.5 turnovers committed per game and 10.2 turnovers forced last year, North Carolina was 120th and 288th in college basketball, respectively.
• East Carolina scored 75.8 points per game (123rd-ranked in college basketball) last season, while ceding 73.8 points per contest (234th-ranked).
• East Carolina was 53rd in the nation with 34.4 rebounds per game. Meanwhile, it ranked 202nd with 31.5 rebounds allowed per contest.
• East Carolina averaged 13.4 assists per game, which ranked them 196th in the country.
• Last season East Carolina committed 10.4 turnovers per game (108th-ranked in college basketball) and forced 11.2 turnovers per contest (184th-ranked).

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