NFL Games This Sunday: Predictions, Odds, Picks, Best Bets for Week 5

The San Francisco 49ers versus the Seattle Seahawks is a game to watch on a Week 5 NFL Sunday slate that has a lot of competitive contests.

Here is the betting info to analyze ahead of Week 5 NFL Sunday.

Jaguars vs. Eagles

The Jacksonville Jaguars (3-1) will take on the Philadelphia Eagles (2-2) on Sunday at 9:30 a.m. ET.

• Game Preview: Philadelphia Eagles vs. Jacksonville Jaguars
• Projected Favorite: Jaguars (73.30% win probability)
• Spread: Jacksonville (-7.5)
• Total: 41.5 -- Over: (-115) | Under: (-105)
• Time: 9:30 a.m. ET
• Channel: NFL Network

Bet on Jacksonville vs. Philadelphia with FanDuel Sportsbook.

Steelers vs. Colts

Star running back Jonathan Taylor and the Indianapolis Colts (2-2) play the Pittsburgh Steelers (2-2) on Sunday at 1 p.m. ET, at Acrisure Stadium.

• Game Preview: Indianapolis Colts at Pittsburgh Steelers
• Projected Favorite: Colts (56.37% win probability)
• Spread: Pittsburgh (-2.5)
• Total: 44.5 -- Over: (-104) | Under: (-118)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Pittsburgh vs. Indianapolis with FanDuel Sportsbook.

Dolphins vs. Bengals

The Cincinnati Bengals (2-2), who were defeated by the Jaguars in their last contest, visit the Miami Dolphins (0-4) at Hard Rock Stadium on Oct. 11 at 1 p.m. ET. The Dolphins lost to the Vikings in their last game.

• Game Preview: Cincinnati Bengals at Miami Dolphins
• Projected Favorite: Bengals (58.80% win probability)
• Spread: Cincinnati (-6.5)
• Total: 42.5 -- Over: (-110) | Under: (-110)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Miami vs. Cincinnati with FanDuel Sportsbook.

Jets vs. Browns

On Sunday, Oct. 11 at 1 p.m. ET, the New York Jets (1-3) will attempt to rebound from their recent 23-12 loss to the Bears when they square off against the Cleveland Browns (3-1) at MetLife Stadium. The Browns won their previous game 27-24 against the Steelers.

• Game Preview: Cleveland Browns at New York Jets
• Projected Favorite: Jets (56.93% win probability)
• Spread: New York (-1.5)
• Total: 40.5 -- Over: (-105) | Under: (-115)
• Time: 1 p.m. ET
• Channel: CBS

Bet on New York vs. Cleveland with FanDuel Sportsbook.

Titans vs. Texans

The Houston Texans (0-4) will visit the Tennessee Titans (0-4) on Sunday at 1 p.m. ET.

• Game Preview: Houston Texans at Tennessee Titans
• Projected Favorite: Texans (72.07% win probability)
• Spread: Houston (-7.5)
• Total: 37.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Tennessee vs. Houston with FanDuel Sportsbook.

Saints vs. Vikings

The Minnesota Vikings (4-0), who defeated the Dolphins in their last game, visit the New Orleans Saints (1-3) at Caesars Superdome on Oct. 11 at 1 p.m. ET. The Saints were defeated by the Falcons in their last game.

• Game Preview: Minnesota Vikings at New Orleans Saints
• Projected Favorite: Vikings (51.33% win probability)
• Spread: Minnesota (-1.5)
• Total: 42.5 -- Over: (-105) | Under: (-115)
• Time: 1 p.m. ET
• Channel: FOX

Bet on New Orleans vs. Minnesota with FanDuel Sportsbook.

Commanders vs. Giants

On Sunday at 1 p.m. ET, the Washington Commanders (1-3) will host the New York Giants (3-1).

• Game Preview: New York Giants at Washington Commanders
• Projected Favorite: Commanders (56.50% win probability)
• Spread: Washington (-3.5)
• Total: 42.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Washington vs. New York with FanDuel Sportsbook.

Patriots vs. Raiders

The Las Vegas Raiders (3-1) will visit the New England Patriots (2-2) on Sunday at 1 p.m. ET.

• Game Preview: Las Vegas Raiders at New England Patriots
• Projected Favorite: Patriots (73.51% win probability)
• Spread: New England (-3.5)
• Total: 44.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: CBS

Bet on New England vs. Las Vegas with FanDuel Sportsbook.

Packers vs. Bears

Christian Watson and the Green Bay Packers (2-2) meet the Chicago Bears (3-1) on Sunday at 1 p.m. ET at Lambeau Field.

• Game Preview: Chicago Bears at Green Bay Packers
• Projected Favorite: Bears (61.29% win probability)
• Spread: Chicago (-2.5)
• Total: 45.5 -- Over: (-110) | Under: (-110)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Green Bay vs. Chicago with FanDuel Sportsbook.

Chargers vs. Broncos

The Los Angeles Chargers (0-4) play on Sunday at 4:05 p.m. ET at SoFi Stadium versus the Denver Broncos (2-2).

• Game Preview: Denver Broncos at Los Angeles Chargers
• Projected Favorite: Broncos (53.03% win probability)
• Spread: Denver (-3.5)
• Total: 42.5 -- Over: (-106) | Under: (-114)
• Time: 4:05 p.m. ET
• Channel: CBS

Bet on Los Angeles vs. Denver with FanDuel Sportsbook.

Cardinals vs. Lions

Star QB Jared Goff and the Detroit Lions (2-2) face the Arizona Cardinals (1-3) on Sunday at 4:25 p.m. ET at State Farm Stadium.

• Game Preview: Detroit Lions at Arizona Cardinals
• Projected Favorite: Lions (66.44% win probability)
• Spread: Detroit (-5.5)
• Total: 54.5 -- Over: (-108) | Under: (-112)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on Arizona vs. Detroit with FanDuel Sportsbook.

Seahawks vs. 49ers

The Seattle Seahawks (3-1) host the San Francisco 49ers (4-0) on Sunday at 4:25 p.m. ET, in a battle between two of the best offensive players in football in wideout Jaxon Smith-Njigba and QB Brock Purdy.

• Game Preview: San Francisco 49ers at Seattle Seahawks
• Projected Favorite: Seahawks (57.37% win probability)
• Spread: Seattle (-3)
• Total: 45.5 -- Over: (-115) | Under: (-105)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on Seattle vs. San Francisco with FanDuel Sportsbook.

Falcons vs. Ravens

Derrick Henry, who ranks fourth-best in the league in rushing yards, will aim to lead the charge for the Baltimore Ravens (3-1) on Oct. 11 at 8:20 p.m. ET, when they visit the Atlanta Falcons (2-2) and their first-ranked run D (48.3 rushing yards allowed per game).

• Game Preview: Baltimore Ravens at Atlanta Falcons
• Projected Favorite: Ravens (52.05% win probability)
• Spread: Atlanta (-3.5)
• Total: 43.5 -- Over: (-114) | Under: (-106)
• Time: 8:20 p.m. ET
• Channel: NBC/Peacock

Bet on Atlanta vs. Baltimore with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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