NFL Games This Sunday: Predictions, Odds, Picks, Best Bets for Week 1

The outings on Sunday in Week 1 of the NFL season are sure to please, including the Dallas Cowboys taking on the New York Giants at MetLife Stadium.

Here's what you need to know in terms of the betting odds for Sunday.

Jaguars vs. Browns

Two of last year's top offensive players will be on display when QB Trevor Lawrence and the Jacksonville Jaguars host pass-catcher Harold Fannin and the Cleveland Browns on Sunday, September 13, 2026.

• Game Preview: Cleveland Browns at Jacksonville Jaguars
• Projected Favorite: Jaguars (77.84% win probability)
• Spread: Jacksonville (-8.5)
• Total: 40.5 -- Over: (-104) | Under: (-118)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Jacksonville vs. Cleveland with FanDuel Sportsbook.

Bengals vs. Buccaneers

One of the top pass-catchers in football last year will be featured when Ja'Marr Chase and the Cincinnati Bengals host the Tampa Bay Buccaneers on Sunday, September 13, 2026.

• Game Preview: Tampa Bay Buccaneers at Cincinnati Bengals
• Projected Favorite: Bengals (52.88% win probability)
• Spread: Cincinnati (-3.5)
• Total: 50.5 -- Over: (-112) | Under: (-108)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Cincinnati vs. Tampa Bay with FanDuel Sportsbook.

Titans vs. Jets

The Tennessee Titans (0-0) host the New York Jets (0-0) at Nissan Stadium on Sunday, Sept. 13 at 1 p.m. ET to start the 2026 NFL season. Last year the Titans missed the playoffs after a 3-14 season, while the Jets went 3-14 and missed the playoffs.

• Game Preview: New York Jets at Tennessee Titans
• Projected Favorite: Titans (52.83% win probability)
• Spread: Tennessee (-1.5)
• Total: 38.5 -- Over: (-110) | Under: (-110)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Tennessee vs. New York with FanDuel Sportsbook.

Lions vs. Saints

The Detroit Lions (0-0) host the New Orleans Saints (0-0) at Ford Field on Sunday, Sept. 13 at 1 p.m. ET to start the 2026 NFL season. Last year the Lions missed the playoffs after a 9-8 season, while the Saints finished 6-11 and missed the playoffs.

• Game Preview: New Orleans Saints at Detroit Lions
• Projected Favorite: Lions (70.00% win probability)
• Spread: Detroit (-6.5)
• Total: 49.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Detroit vs. New Orleans with FanDuel Sportsbook.

Texans vs. Bills

The Buffalo Bills (0-0) visit the Houston Texans (0-0) at NRG Stadium on Sunday, Sept. 13 at 1 p.m. ET to begin the 2026 NFL season.

• Game Preview: Buffalo Bills at Houston Texans
• Projected Favorite: Bills (52.23% win probability)
• Spread: Buffalo (-1.5)
• Total: 44.5 -- Over: (-110) | Under: (-110)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Houston vs. Buffalo with FanDuel Sportsbook.

Colts vs. Ravens

Zay Flowers and the Baltimore Ravens will visit Jonathan Taylor and the Indianapolis Colts on Sunday at 1 p.m. ET, in a battle between two of the top offensive players in football last year.

• Game Preview: Baltimore Ravens at Indianapolis Colts
• Projected Favorite: Ravens (57.21% win probability)
• Spread: Baltimore (-3.5)
• Total: 47.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Indianapolis vs. Baltimore with FanDuel Sportsbook.

Steelers vs. Falcons

One of the top pass-catchers in football last season will be on display when Kyle Pitts and the Atlanta Falcons visit the Pittsburgh Steelers on Sunday, September 13, 2026.

• Game Preview: Atlanta Falcons at Pittsburgh Steelers
• Projected Favorite: Steelers (59.76% win probability)
• Spread: Pittsburgh (-5.5)
• Total: 40.5 -- Over: (-118) | Under: (-104)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Pittsburgh vs. Atlanta with FanDuel Sportsbook.

Panthers vs. Bears

The Chicago Bears (0-0) and the Carolina Panthers (0-0) begin the 2026 NFL season on Sunday, Sept. 13, with kickoff set for 1 p.m. ET at Bank of America Stadium. The Bears are coming off an 11-6 season that saw them lose in the Divisional round, while the Panthers went 8-9 last year and lost in the Wild Card round.

• Game Preview: Chicago Bears at Carolina Panthers
• Projected Favorite: Bears (55.18% win probability)
• Spread: Chicago (-3)
• Total: 47.5 -- Over: (-102) | Under: (-120)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Carolina vs. Chicago with FanDuel Sportsbook.

Chargers vs. Cardinals

One of the top pass-catchers in football last season will be on display when Trey McBride and the Arizona Cardinals visit the Los Angeles Chargers on Sunday, September 13, 2026.

• Game Preview: Arizona Cardinals at Los Angeles Chargers
• Projected Favorite: Chargers (76.31% win probability)
• Spread: Los Angeles (-9.5)
• Total: 47.5 -- Over: (-102) | Under: (-120)
• Time: 4:25 p.m. ET
• Channel: CBS

Bet on Los Angeles vs. Arizona with FanDuel Sportsbook.

Raiders vs. Dolphins

One of the best pass-catchers in football last year will be on display when De'Von Achane and the Miami Dolphins visit the Las Vegas Raiders on Sunday, September 13, 2026.

• Game Preview: Miami Dolphins at Las Vegas Raiders
• Projected Favorite: Dolphins (50.71% win probability)
• Spread: Las Vegas (-3)
• Total: 39.5 -- Over: (-118) | Under: (-104)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on Las Vegas vs. Miami with FanDuel Sportsbook.

Eagles vs. Commanders

At 4:25 p.m. ET on Sunday, the Washington Commanders play at the Philadelphia Eagles.

• Game Preview: Washington Commanders at Philadelphia Eagles
• Projected Favorite: Eagles (69.94% win probability)
• Spread: Philadelphia (-5.5)
• Total: 44.5 -- Over: (-105) | Under: (-115)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on Philadelphia vs. Washington with FanDuel Sportsbook.

Vikings vs. Packers

The Minnesota Vikings will host the Green Bay Packers on Sunday at 4:25 p.m. ET.

• Game Preview: Green Bay Packers at Minnesota Vikings
• Projected Favorite: Packers (52.76% win probability)
• Spread: Minnesota (-1.5)
• Total: 46.5 -- Over: (-110) | Under: (-110)
• Time: 4:25 p.m. ET
• Channel: CBS

Bet on Minnesota vs. Green Bay with FanDuel Sportsbook.

Giants vs. Cowboys

The Dallas Cowboys (0-0) visit the New York Giants (0-0) at MetLife Stadium on Sunday, Sept. 13 at 8:20 p.m. ET to start the 2026 NFL season.

• Game Preview: Dallas Cowboys at New York Giants
• Projected Favorite: Cowboys (62.78% win probability)
• Spread: Dallas (-3)
• Total: 48.5 -- Over: (-105) | Under: (-115)
• Time: 8:20 p.m. ET
• Channel: NBC/Peacock

Bet on New York vs. Dallas with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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