Lions vs Saints Prediction, Odds, Picks, Best Bets for NFL Week 1

The Detroit Lions versus the New Orleans Saints is on the NFL schedule for Sunday.
We've got you covered, in terms of the most important info about NFL betting lines, before you make your wager on FanDuel Sportsbook.
Lions vs Saints Prediction & Pick
All NFL win probability predictions and picks are according to numberFire.
Prediction: Lions win (70%)
Lions vs Saints Point Spread
The Lions are 6.5-point favorites against the Saints. The Lions are -122 to cover the spread, while the Saints are +100 to cover as a 6.5-point underdog.
Lions vs Saints Over/Under
The Lions-Saints matchup on Sept. 13 has been given an over/under of 49.5 points. The over is -115 and the under is -105.
Lions vs Saints Moneyline
The Lions vs Saints moneyline has Detroit as a -334 favorite, while New Orleans is a +270 underdog on the road.
Lions vs Saints Betting Trends
- The Lions were 8-9-0 against the spread last year.
- As 6.5-point favorites or greater, the Lions went 4-4 against the spread last season.
- Out of 17 Detroit games last year, 10 hit the over.
- The Saints' record against the spread last season was 9-8-0.
- New Orleans won twice ATS (2-3) as underdogs of 6.5 points or more last year.
- The Saints had five of their 17 games go over the point total last year.
Check out even more in-depth Lions vs. Saints analysis on FanDuel Research.
Lions vs Saints Odds & Spread
- All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: DET: (-334) | NO: (+270)
- Spread: DET: -6.5 (-122) | NO: +6.5 (100)
- Total: 49.5 -- Over: (-115) | Under: (-105)
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