Lions vs Saints Prediction, Odds, Picks, Best Bets for NFL Week 1

The Detroit Lions versus the New Orleans Saints is on the NFL schedule for Sunday.

Get the latest NFL odds ahead of this game on FanDuel Sportsbook.

Lions vs Saints Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Lions win (70%)

Lions vs Saints Point Spread

The Lions are 6.5-point favorites against the Saints. The Lions are -122 to cover the spread, while the Saints are +100 to cover as a 6.5-point underdog.

Lions vs Saints Over/Under

A total of 49.5 points has been set for the Lions-Saints matchup on Sept. 13, with the over available at -115 and the under at -105.

Lions vs Saints Moneyline

Looking at the moneyline for Lions-Saints, Detroit is the favorite at -334, and New Orleans is +270 playing on the road.

Lions vs Saints Betting Trends

• The Lions covered the spread eight times in 17 games last season.
• The Lions had an ATS record of 4-4 as 6.5-point favorites or greater last year.
• In 17 Detroit games last year, 10 hit the over.
• The Saints posted a 9-8-0 record against the spread last year.
• As 6.5-point underdogs or more, New Orleans had two wins ATS (2-3) last year.
• Last season, five of the Saints' 17 games went over the point total.

Check out even more in-depth Lions vs. Saints analysis on FanDuel Research.

Lions vs Saints Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-334) | NO: (+270)
• Spread: DET: -6.5 (-122) | NO: +6.5 (100)
• Total: 49.5 -- Over: (-115) | Under: (-105)

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