Nebraska vs Northwestern Prediction, Odds, Picks, Best Bets for Week 9 2025

College football's Saturday slate includes the Nebraska Cornhuskers taking on the Northwestern Wildcats.

Get the latest NCAA football odds ahead of this matchup on FanDuel Sportsbook.

Nebraska vs Northwestern Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Nebraska: (-295) | Northwestern: (+240)
• Spread: Nebraska: -7.5 (-106) | Northwestern: +7.5 (-114)
• Total: 44.5 -- Over: (-110) | Under: (-110)

Nebraska vs Northwestern Betting Trends

• Nebraska has won twice against the spread this season.
• As at least a 7.5-point favorite, Nebraska has two wins ATS (2-2).
• Out of seven Nebraska games so far this season, five have gone over the total.
• Northwestern has five wins in seven contests against the spread this year.
• Northwestern is unbeaten ATS (2-0) as a 7.5-point underdog or more this year.
• Northwestern has had one game (of seven) hit the over this year.

Nebraska vs Northwestern Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Cornhuskers win (73.2%)

Nebraska vs Northwestern Point Spread

Nebraska is favored by 7.5 points against Northwestern. Nebraska is -106 to cover the spread, while Northwestern is -114.

Nebraska vs Northwestern Over/Under

The Nebraska-Northwestern game on Oct. 25 has been given an over/under of 44.5 points. The over is -110 and the under is -110.

Nebraska vs Northwestern Moneyline

Looking at the moneyline for Northwestern-Nebraska, Northwestern is the underdog at +240, and Nebraska is -295.

Nebraska vs. Northwestern Points Insights

Nebraska vs. Northwestern Game Info

• Game day: Saturday, October 25, 2025
• Game time: 12 p.m. ET
• TV channel: Fox Sports 1
• Location: Lincoln, Nebraska
• Stadium: Memorial Stadium (Lincoln, NE)

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Check out even more in-depth Nebraska vs. Northwestern analysis on FanDuel Research.