Wednesday’s MLB Odds, Betting Lines and Predictions - April 16

In a Wednesday MLB schedule that features plenty of compelling matchups, the Chicago Cubs versus the San Diego Padres is a game to see. For predictions on every game on the slate, check out the article below.
Today's MLB Odds and Predictions
Atlanta Braves at Toronto Blue Jays Odds, Lines & Predictions
Game Info
- When: 1:07 PM ET
- Where: Rogers Centre
- TV Channel: SNET and FDSSO
- Probable Pitchers: Chris Bassitt vs. Spencer Strider
- Records: Blue Jays (11-8), Braves (5-13)
- Braves Moneyline Odds: -126
- Blue Jays Moneyline Odds: +108
numberFire Prediction
- numberFire Predicted Favorite: Blue Jays
- Blue Jays Win Probability: 57.28%
- Braves Win Probability: 42.72%
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New York Mets at Minnesota Twins Odds, Lines & Predictions
Game Info
- When: 1:10 PM ET
- Where: Target Field
- TV Channel: MNNT and SNY
- Probable Pitchers: David Festa vs. Huascar Brazoban
- Records: Twins (7-12), Mets (11-7)
- Twins Moneyline Odds: -122
- Mets Moneyline Odds: +104
numberFire Prediction
- numberFire Predicted Favorite: Mets
- Mets Win Probability: 50.39%
- Twins Win Probability: 49.61%
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Detroit Tigers at Milwaukee Brewers Odds, Lines & Predictions
Game Info
- When: 1:10 PM ET
- Where: American Family Field
- TV Channel: FDSWI and FDSDET
- Probable Pitchers: José Quintana vs. Keider Montero
- Records: Brewers (10-9), Tigers (10-8)
- Brewers Moneyline Odds: -154
- Tigers Moneyline Odds: +130
numberFire Prediction
- numberFire Predicted Favorite: Brewers
- Brewers Win Probability: 61.68%
- Tigers Win Probability: 38.32%
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Houston Astros at St. Louis Cardinals Odds, Lines & Predictions
Game Info
- When: 1:15 PM ET
- Where: Busch Stadium
- TV Channel: FDSMW and SCHN2
- Probable Pitchers: Steven Matz vs. Ronel Blanco
- Records: Cardinals (9-9), Astros (8-10)
- Cardinals Moneyline Odds: -112
- Astros Moneyline Odds: -104
numberFire Prediction
- numberFire Predicted Favorite: Astros
- Astros Win Probability: 53.46%
- Cardinals Win Probability: 46.54%
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Chicago Cubs at San Diego Padres Odds, Lines & Predictions
Game Info
- When: 4:10 PM ET
- Where: PETCO Park
- TV Channel: SDPA and MARQ
- Probable Pitchers: Nick Pivetta vs. Matthew Boyd
- Records: Padres (15-4), Cubs (12-9)
- Padres Moneyline Odds: -108
- Cubs Moneyline Odds: -108
numberFire Prediction
- numberFire Predicted Favorite: Padres
- Padres Win Probability: 56.19%
- Cubs Win Probability: 43.81%
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Cleveland Guardians at Baltimore Orioles Odds, Lines & Predictions
Game Info
- When: 6:35 PM ET
- Where: Oriole Park at Camden Yards
- TV Channel: MASN2 and CLEG
- Probable Pitchers: Dean Kremer vs. Gavin Williams
- Records: Orioles (6-10), Guardians (9-7)
- Orioles Moneyline Odds: -124
- Guardians Moneyline Odds: +106
numberFire Prediction
- numberFire Predicted Favorite: Orioles
- Orioles Win Probability: 51.14%
- Guardians Win Probability: 48.86%
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Washington Nationals at Pittsburgh Pirates Odds, Lines & Predictions
Game Info
- When: 6:40 PM ET
- Where: PNC Park
- TV Channel: SportsNet PT and MASN
- Probable Pitchers: Bailey Falter vs. Mitchell Parker
- Records: Pirates (6-12), Nationals (7-10)
- Pirates Moneyline Odds: -112
- Nationals Moneyline Odds: -104
numberFire Prediction
- numberFire Predicted Favorite: Pirates
- Pirates Win Probability: 52.58%
- Nationals Win Probability: 47.42%
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Arizona Diamondbacks at Miami Marlins Odds, Lines & Predictions
Game Info
- When: 6:40 PM ET
- Where: loanDepot park
- TV Channel: FDSFL and ARID
- Probable Pitchers: Max Meyer vs. Brandon Pfaadt
- Records: Marlins (8-8), Diamondbacks (10-7)
- Diamondbacks Moneyline Odds: -146
- Marlins Moneyline Odds: +124
numberFire Prediction
- numberFire Predicted Favorite: Diamondbacks
- Diamondbacks Win Probability: 63.25%
- Marlins Win Probability: 36.75%
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Seattle Mariners at Cincinnati Reds Odds, Lines & Predictions
Game Info
- When: 6:40 PM ET
- Where: Great American Ball Park
- TV Channel: Fox Sports 1, FDSOH and ROOT Sports NW
- Probable Pitchers: Nick Martínez vs. Bryce Miller
- Records: Reds (9-8), Mariners (8-9)
- Mariners Moneyline Odds: -112
- Reds Moneyline Odds: -104
numberFire Prediction
- numberFire Predicted Favorite: Mariners
- Mariners Win Probability: 51.70%
- Reds Win Probability: 48.30%
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San Francisco Giants at Philadelphia Phillies Odds, Lines & Predictions
Game Info
- When: 6:45 PM ET
- Where: Citizens Bank Park
- TV Channel: NBCS-PH and NBCS-BA
- Probable Pitchers: Aaron Nola vs. Robbie Ray
- Records: Phillies (10-7), Giants (12-5)
- Phillies Moneyline Odds: -146
- Giants Moneyline Odds: +124
numberFire Prediction
- numberFire Predicted Favorite: Phillies
- Phillies Win Probability: 66.58%
- Giants Win Probability: 33.42%
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Kansas City Royals at New York Yankees Odds, Lines & Predictions
Game Info
- When: 7:05 PM ET
- Where: Yankee Stadium
- TV Channel: Amazon Prime Video and FDSKC
- Probable Pitchers: Clarke Schmidt vs. Kris Bubic
- Records: Yankees (10-7), Royals (8-10)
- Yankees Moneyline Odds: -156
- Royals Moneyline Odds: +132
numberFire Prediction
- numberFire Predicted Favorite: Yankees
- Yankees Win Probability: 53.34%
- Royals Win Probability: 46.66%
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Boston Red Sox at Tampa Bay Rays Odds, Lines & Predictions
Game Info
- When: 7:05 PM ET
- Where: George M. Steinbrenner Field
- TV Channel: FDSSUN and NESN
- Probable Pitchers: Zack Littell vs. Sean Newcomb
- Records: Rays (8-9), Red Sox (9-10)
- Rays Moneyline Odds: -134
- Red Sox Moneyline Odds: +114
numberFire Prediction
- numberFire Predicted Favorite: Rays
- Rays Win Probability: 56.10%
- Red Sox Win Probability: 43.90%
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Athletics at Chicago White Sox Odds, Lines & Predictions
Game Info
- When: 7:40 PM ET
- Where: Rate Field
- TV Channel: CHSN and NBCS-CA
- Probable Pitchers: Jonathan Cannon vs. Osvaldo Bido
- Records: White Sox (4-12), Athletics (7-10)
- Athletics Moneyline Odds: -156
- White Sox Moneyline Odds: +132
numberFire Prediction
- numberFire Predicted Favorite: Athletics
- Athletics Win Probability: 57.03%
- White Sox Win Probability: 42.97%
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Los Angeles Angels at Texas Rangers Odds, Lines & Predictions
Game Info
- When: 8:05 PM ET
- Where: Globe Life Field
- TV Channel: RSN and FDSW
- Probable Pitchers: Patrick Corbin vs. José Soriano
- Records: Rangers (10-7), Angels (9-7)
- Angels Moneyline Odds: -134
- Rangers Moneyline Odds: +114
numberFire Prediction
- numberFire Predicted Favorite: Rangers
- Rangers Win Probability: 52.01%
- Angels Win Probability: 47.99%
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Colorado Rockies at Los Angeles Dodgers Odds, Lines & Predictions
Game Info
- When: 10:10 PM ET
- Where: Dodger Stadium
- TV Channel: SportsNet LA and COLR
- Probable Pitchers: Bobby Miller vs. German Márquez
- Records: Dodgers (13-6), Rockies (3-14)
- Dodgers Moneyline Odds: -310
- Rockies Moneyline Odds: +250
numberFire Prediction
- numberFire Predicted Favorite: Dodgers
- Dodgers Win Probability: 66.31%
- Rockies Win Probability: 33.69%
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All MLB win probability predictions and picks are according to numberFire.



