Mississippi State vs Wake Forest Prediction, Odds, Picks, Best Bets for Duke's Mayo Bowl 2025

Friday's slate in college football includes a matchup between the Mississippi State Bulldogs and the Wake Forest Demon Deacons.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

Mississippi State vs Wake Forest Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Mississippi State: (-132) | Wake Forest: (+110)
• Spread: Mississippi State: -2.5 (-110) | Wake Forest: +2.5 (-110)
• Total: 56.5 -- Over: (-110) | Under: (-110)

Mississippi State vs Wake Forest Betting Trends

• Mississippi State's record against the spread is 8-4-0.
• Mississippi State has yet to lose ATS (3-0) as a 2.5-point favorite or greater this year.
• Mississippi State has played 12 games this season, and six of them have gone over the total.
• Wake Forest is 8-4-0 against the spread this season.
• Against the spread as 2.5-point underdogs or greater, Wake Forest is 4-3.
• There have been seven Wake Forest games (out of 12) that hit the over this season.

Mississippi State vs Wake Forest Point Spread

Wake Forest is the underdog by 2.5 points against Mississippi State. Wake Forest is -110 to cover the spread, and Mississippi State is -110.

Mississippi State vs Wake Forest Over/Under

The over/under for Mississippi State-Wake Forest on Jan. 2 is 56.5. The over is -110, and the under is -110.

Mississippi State vs Wake Forest Moneyline

Looking at the moneyline for Wake Forest-Mississippi State, Wake Forest is the underdog at +110, and Mississippi State is -132.

Mississippi State vs. Wake Forest Points Insights

Mississippi State vs. Wake Forest Game Info

• Game day: Friday, January 2, 2026
• Game time: 8 p.m. ET
• TV channel: ESPN
• Location: Charlotte, North Carolina
• Stadium: Bank of America Stadium

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Check out even more in-depth Mississippi State vs. Wake Forest analysis on FanDuel Research.