Mississippi State vs Wake Forest Prediction, Odds, Picks, Best Bets for Duke's Mayo Bowl 2025

The Mississippi State Bulldogs are among the college football teams playing on Friday, versus the Wake Forest Demon Deacons.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the most important information about today's NCAA football betting odds.

Mississippi State vs Wake Forest Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Mississippi State: (-152) | Wake Forest: (+128)
• Spread: Mississippi State: -3.5 (-102) | Wake Forest: +3.5 (-120)
• Total: 53.5 -- Over: (-110) | Under: (-110)

Mississippi State vs Wake Forest Betting Trends

• Mississippi State is 8-4-0 against the spread this season.
• Against the spread as 3.5-point or better favorites, Mississippi State is 3-0.
• Mississippi State has played 12 games this year, and six of them have hit the over.
• Wake Forest has beaten the spread eight times in 12 games.
• Wake Forest is 4-2 as 3.5-point or bigger underdogs in 2025.
• Of 12 Wake Forest games so far this season, seven have gone over the total.

Mississippi State vs Wake Forest Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Demon Deacons win (50%)

Mississippi State vs Wake Forest Point Spread

Wake Forest is the underdog by 3.5 points against Mississippi State. Wake Forest is -102 to cover the spread, and Mississippi State is -120.

Mississippi State vs Wake Forest Over/Under

Mississippi State versus Wake Forest on Jan. 2 has an over/under of 53.5 points, with the over -110 and the under -110.

Mississippi State vs Wake Forest Moneyline

Mississippi State is a -152 favorite on the moneyline, while Wake Forest is a +128 underdog.

Mississippi State vs. Wake Forest Points Insights

Mississippi State vs. Wake Forest Game Info

• Game day: Friday, January 2, 2026
• Game time: 8 p.m. ET
• TV channel: ESPN
• Location: Charlotte, North Carolina
• Stadium: Bank of America Stadium

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Check out even more in-depth Mississippi State vs. Wake Forest analysis on FanDuel Research.