Michael Pittman Jr. Fantasy Football Week 16: Stats and Projections vs. 49ers

Michael Pittman Jr. and the Indianapolis Colts will play the San Francisco 49ers and their 23rd-ranked passing defense (227.6 yards conceded per game) in Week 16, on Monday at 8:15 p.m. ET.

With Pittman's next game versus the 49ers, should you consider him for your DFS lineup? See below for more stats and information.

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Michael Pittman Jr. Week 16 Fantasy Football Projection

• Matchup: Indianapolis Colts vs. San Francisco 49ers
• Game Date: December 22, 2025
• Game Time: 8:15 p.m.
• Projected Fantasy Points: 4.8
• PPR Projected Fantasy Points: 7.2
• Projected Receiving Yards: 33.04
• Projected Receiving TDs: 0.22

Projections provided by numberFire

Pittman Fantasy Performance

• With 116.5 fantasy points in 2025 (8.3 per game), Pittman is the 22nd-ranked fantasy player at his position and 95th overall.
• In his last three games, Pittman has produced 11.8 fantasy points (3.9 per game), as he's converted 21 targets into 13 catches for 118 yards and zero TDs.
• Pittman has been targeted 31 times, with 20 receptions for 164 yards and one TD, in his last five games. He has put up 22.4 fantasy points (4.5 per game) during that period.
• The peak of Pittman's fantasy season came against the Tennessee Titans in Week 8, when he racked up 15.5 fantasy points with zero passing yards, zero TDs, and picks.
• From a fantasy standpoint, Michael Pittman Jr.'s matchup against the Houston Texans in Week 13 was his worst of the year, as he put up just 1.3 fantasy points. He tallied one reception for 13 yards on the day.

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49ers Defensive Performance

• San Francisco has allowed over 300 yards passing to three players this year.
• A total of 13 players have thrown for at least one TD versus the 49ers this year.
• San Francisco has allowed eight players to throw for two or more touchdowns in a game this season.
• The 49ers have allowed at least three passing touchdowns to three opposing QBs this year.
• San Francisco has allowed three players to amass more than 100 yards receiving in a game this year.
• The 49ers have allowed 24 players to catch a touchdown pass versus them this season.
• San Francisco has allowed only one player to catch two or more TD passes in a game this year.
• The 49ers have given up more than 100 yards rushing to just two players this season.
• A total of eight players have rushed for at least one TD against San Francisco this year.
• The 49ers have given up at least two rushing touchdowns to only one player this season.

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