Maple Leafs vs Sabres NHL Prediction, Odds, Picks, Best Bets for Oct. 25

NHL action on Saturday includes the Toronto Maple Leafs taking on the Buffalo Sabres.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NHL moneyline insights you need to know.

Maple Leafs vs Sabres Game Info

• Toronto Maple Leafs (3-4-1) vs. Buffalo Sabres (4-4)
• Date: Saturday, October 25, 2025
• Time: 5 p.m. ET
• Venue: Scotiabank Arena -- Toronto, Ontario
• Coverage: ESPN+

Maple Leafs vs Sabres Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Maple Leafs vs Sabres Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Maple Leafs win (53.8%)

Maple Leafs vs Sabres Puck Line

• The Sabres are underdogs by 1.5 goals. The Sabres are -215 to cover the spread, and the Maple Leafs are +172.

Maple Leafs vs Sabres Over/Under

• The Maple Leafs-Sabres game on Oct. 25 has been given an over/under of 6.5 goals. The over is -108 and the under is -112.

Maple Leafs vs Sabres Moneyline

• Looking at the moneyline for Maple Leafs-Sabres, Toronto is the favorite at -140, and Buffalo is +116 playing on the road.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!