Louisville vs Wake Forest College Basketball Prediction, Odds, Picks, Best Bets for Feb. 7

The Wake Forest Demon Deacons (11-11, 2-7 ACC) will try to break a four-game losing streak when they host the Louisville Cardinals (16-6, 6-4 ACC) on February 7, 2026 at Lawrence Joel Veterans Memorial Coliseum.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Louisville vs. Wake Forest Game Info and Odds

• Game day: Saturday, February 7, 2026
• Game time: 12 p.m. ET
• TV channel: ACC Network
• Location: Winston-Salem, North Carolina
• Arena: Lawrence Joel Veterans Memorial Coliseum

Louisville vs. Wake Forest Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Louisville win (75.3%)

See these betting trends and insights before you bet on Saturday's Louisville-Wake Forest spread (Louisville -9.5) or over/under (160.5 points).

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Louisville vs. Wake Forest: ATS Betting Stats and Trends

• Louisville has won 12 games against the spread this season, while failing to cover 10 times.
• Wake Forest has won seven games against the spread this year, while failing to cover 15 times.
• Louisville (7-4) covers a higher percentage of games when it is favored by 9.5 points or more this season (63.6%) than Wake Forest (3-2) does as a 9.5+-point underdog (60%).
• The Cardinals have covered the spread in a higher percentage of their home games than road games. They have covered eight times in 14 opportunities at home, and they've covered two times in six opportunities on the road.
• Against the spread, the Demon Deacons have performed better at home (3-10-0) than away (1-4-0).
• Louisville is 4-6-0 against the spread in conference action this year.
• Wake Forest has won once against the spread in ACC games this season.

Louisville vs. Wake Forest: Moneyline Betting Stats

• Louisville has come away with 10 wins in the 13 contests it has been listed as the moneyline favorite in this season.
• The Cardinals have yet to lose in five games when named as moneyline favorite of -581 or better.
• Wake Forest has been the moneyline underdog 10 total times this season. Wake Forest has gone 1-9 in those games.
• The Demon Deacons have played in four games as a moneyline underdog with odds of +420 or longer without earning a win.
• Louisville has an implied victory probability of 85.3% according to the moneyline set by sportsbooks for this matchup.

Louisville vs. Wake Forest Head-to-Head Comparison

• Last season, Louisville was 65th in the country on offense (78.5 points scored per game) and 89th defensively (69.5 points conceded).
• Last season, Louisville was 47th in the country in rebounds (34.6 per game) and 114th in rebounds conceded (30.2).
• Louisville was 148th in the nation in assists (13.9 per game) last year.
• Last year, Louisville was 150th in the country in turnovers committed (10.9 per game) and 93rd in turnovers forced (12.2).
• Wake Forest averaged 70.2 points per game (275th-ranked in college basketball) last year, while allowing 68 points per contest (56th-ranked).
• Wake Forest was 282nd in college basketball with 30.3 rebounds per game. Meanwhile, it ranked 217th with 31.8 rebounds allowed per game.
• Wake Forest ranked 330th in the nation with 11.3 assists per game.
• Wake Forest was 143rd in college basketball with 10.8 turnovers per game last season. Meanwhile, it ranked 58th with 12.8 forced turnovers per game.

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