Louisville vs Bowling Green Prediction, Odds, Picks, Best Bets for Week 4 2025

On Saturday in college football, the Louisville Cardinals are up against the Bowling Green Falcons.

We've got you covered, in terms of the vital information regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Louisville vs Bowling Green Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Louisville: (-4545) | Bowling Green: (+1600)
• Spread: Louisville: -26.5 (-105) | Bowling Green: +26.5 (-115)
• Total: 51.5 -- Over: (-105) | Under: (-115)

Louisville vs Bowling Green Betting Trends

• Louisville has no wins against the spread this year.
• Louisville is winless ATS (0-1) as a 26.5-point favorite or greater this season.
• One of two Louisville games have hit the over this year.
• Bowling Green has won twice against the spread this year.
• One Bowling Green game (out of three) has hit the over this year.

Louisville vs Bowling Green Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (88.9%)

Louisville vs Bowling Green Point Spread

Louisville is favored by 26.5 points against Bowling Green. Louisville is -105 to cover the spread, while Bowling Green is -115.

Louisville vs Bowling Green Over/Under

The over/under for the Louisville versus Bowling Green game on Sept. 20 has been set at 51.5, with -105 odds on the over and -115 odds on the under.

Louisville vs Bowling Green Moneyline

Looking at the moneyline for Bowling Green-Louisville, Bowling Green is the underdog at +1600, and Louisville is -4545.

Louisville vs. Bowling Green Points Insights

Louisville vs. Bowling Green Game Info

• Game day: Saturday, September 20, 2025
• Game time: 12 p.m. ET
• TV channel: ACC Network
• Location: Louisville, Kentucky
• Stadium: L&N Federal Credit Union Stadium

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