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2025 Louisville Football Odds and Schedule

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2025 Louisville Football Odds and Schedule

Odds updated as of 6:45 a.m.

The Louisville Cardinals' 2025 record sits at 8-4. Take a look at their full schedule and results in the article below.

Louisville 2025 Schedule

Week
Opponent
Date
Score
Favorite
Total
1Eastern KentuckyAug. 30W 51-17Cardinals (-38.5)56.5
2James MadisonSept. 5W 28-14Cardinals (-14.5)55.5
4Bowling GreenSept. 20W 40-17Cardinals (-26.5)51.5
5@ PittsburghSept. 27W 34-27Cardinals (-3.5)55.5
6VirginiaOct. 4L 30-27Cardinals (-6.5)59.5
8@ Miami (FL)Oct. 17W 24-21Hurricanes (-11.5)49.5
9Boston CollegeOct. 25W 38-24Cardinals (-25.5)54.5

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Louisville Last Game

The Cardinals go into their next matchup after winning 41-0 over the Kentucky Wildcats in their last game on Nov. 29. Against the Wildcats, Miller Moss led the Cards with 182 yards on 12-of-20 passing (60.0%) for three TDs and no interceptions. He also carried the ball four times for 18 yards and one rushing touchdown. In the running game, Braxton Jennings totaled 113 rushing yards on 20 carries (5.7 yards per carry). In the receiving game, Jacob Stewart had 43 yards on one catch (43.0 per reception) with one touchdown in that game.

Louisville Betting Insights

  • Louisville has won six of the nine games it was the moneyline favorite this season (66.7%).
  • The Cardinals have put together a 6-3 record in games they were favored on the moneyline (winning 66.7% of those games).

Find more stats and analysis about Louisville on FanDuel Research!

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