Lafayette vs Holy Cross College Basketball Prediction, Odds, Picks, Best Bets for Patriot League Tournament

The No. 7 seed Lafayette Leopards (11-20, 8-10 Patriot League) and the No. 2 seed Holy Cross Crusaders (10-21, 5-13 Patriot League) will look to advance in the Patriot League tournament on Tuesday as they square off at 7 p.m. ET.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Lafayette vs. Holy Cross Game Info and Odds

• Game day: Tuesday, March 3, 2026
• Game time: 7 p.m. ET
• TV channel: ESPN+
• Location: Easton, Pennsylvania
• Arena: Kirby Sports Center

Lafayette vs. Holy Cross Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Lafayette win (58.2%)

Before making a wager on Tuesday's Lafayette-Holy Cross spread (Lafayette -4.5) or total (141.5 points), check out the betting trends and insights below.

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Lafayette vs. Holy Cross: ATS Betting Stats and Trends

• Lafayette has compiled a 14-16-0 ATS record so far this year.
• Holy Cross has won 14 games against the spread this season, while failing to cover 15 times.
• Lafayette hasn't covered the spread as a 4.5-point favorite or more this season, while Holy Cross covers as an underdog of 4.5 or more 52.9% of the time.
• The Leopards have done a better job covering the spread in away games (10-6-0) than they have at home (4-10-0).
• The Crusaders have been better against the spread at home (6-6-0) than away (7-9-0) this year.
• Lafayette has covered the spread eight times in 18 conference games.
• Holy Cross has beaten the spread eight times in 18 Patriot League games.

Lafayette vs. Holy Cross: Moneyline Betting Stats

• Lafayette has come away with six wins in the 10 contests it has been listed as the moneyline favorite in this season.
• The Leopards have yet to play a game this season with better moneyline odds than -225.
• Holy Cross is 7-18 in games it was the underdog on the moneyline (winning 28% of those games).
• In games they have played as a moneyline underdog with odds of +184 or longer, the Crusaders have a 3-11 record (winning only 21.4% of their games).
• Oddsmakers have implied with the moneyline set for this matchup that Lafayette has a 69.2% chance of pulling out a win.

Lafayette vs. Holy Cross Head-to-Head Comparison

• With 68.5 points scored per game and 68.9 points allowed last year, Lafayette was 313th in college basketball offensively and 79th defensively.
• Lafayette collected 31.3 rebounds per game and gave up 32.8 boards last year, ranking 214th and 283rd, respectively, in the nation.
• Last season Lafayette was ranked 93rd in college basketball in assists with 14.7 per game.
• In terms of turnovers, Lafayette was 120th in college basketball in committing them (10.5 per game) last season. It was 225th in forcing them (10.8 per game).
• With 69.6 points per game on offense, Holy Cross was 294th in college basketball last season. At the other end of the court, it allowed 72.1 points per contest, which ranked 185th in college basketball.
• Holy Cross averaged 29.7 rebounds per game (310th-ranked in college basketball) last year, while allowing 31.1 rebounds per contest (172nd-ranked).
• Holy Cross dished out 12.4 dimes per game, which ranked them 268th in the country.
• Holy Cross ranked 186th in the country at 11.2 turnovers per contest, but it forced 8.9 turnovers per game, which ranked 13th-worst in college basketball.

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