Knicks vs. 76ers Prediction, Odds, Picks, Best Bets for Dec. 19

Knicks vs. 76ers Game Info

• Date: Friday, December 19, 2025
• Time: 7 p.m. ET
• Venue: Madison Square Garden -- New York City, New York
• Coverage: Amazon Prime Video and MSG

Jalen Brunson and the New York Knicks (19-7) are 7.5-point favorites against Tyrese Maxey and the Philadelphia 76ers (14-11) Friday, December 19, 2025 at Madison Square Garden. The matchup begins at 7 p.m. ET on Amazon Prime Video and MSG. The over/under in the matchup is 228.5.

Knicks vs. 76ers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Knicks vs. 76ers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Knicks win (73.5%)

Knicks vs. 76ers Betting Trends

• The Knicks have put together a 16-9-1 record against the spread this season.
• The 76ers have played 25 games, with 13 wins against the spread.
• Games involving the Knicks have hit the over 14 times out of 25 chances this season.
• The 76ers have eclipsed the over/under 48% of the time this year (12 of 25 games with a set point total).
• New York sports a better record against the spread at home (13-1-0) than it does in road games (3-8-1).
• The Knicks have hit the over on the over/under in a higher percentage of home games (57.1%) than road tilts (50%).
• Against the spread, Philadelphia has had better results away (7-3-0) than at home (6-8-1).
• 76ers games have gone above the over/under 40% of the time at home (six of 15), and 60% of the time on the road (six of 10).

Knicks Leaders

• Karl-Anthony Towns averages 22.4 points, 11.9 rebounds and 3.2 assists, shooting 47.4% from the field and 36% from downtown, with 1.9 made treys per contest.
• Brunson is averaging 28.7 points, 6.4 assists and 3.3 boards.
• Mikal Bridges is averaging 16.6 points, 4.7 boards and 4.2 assists. At the other end, he averages 1.8 steals (fourth in league) and 1.1 blocked shots.
• Josh Hart is averaging 12.4 points, 7.7 boards and 5 assists. Defensively, he averages 1.4 steals and 0.3 blocked shots.
• OG Anunoby's numbers on the season are 16.2 points, 5.4 boards and 1.9 assists per game, shooting 48.1% from the floor and 40% from beyond the arc, with an average of 2.5 made treys.

76ers Leaders

• Maxey is averaging 31.5 points, 4.7 rebounds and 7.2 assists for the 76ers.
• Quentin Grimes' numbers on the season are 16.2 points, 4.2 rebounds and 4.5 assists per game. He is draining 44% of his shots from the floor and 36.9% from 3-point range, with an average of 2.4 triples.
• The 76ers are getting 15.2 points, 5.6 boards and 4 assists per game from VJ Edgecombe.
• The 76ers receive 7.3 points per game from Andre Drummond, plus 9.4 rebounds and 0.9 assists.
• Per game, Joel Embiid provides the 76ers 20.5 points, 6.6 rebounds and 2.8 assists, plus 0.8 steals and 1.3 blocks.

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