Jonathan Taylor Fantasy Football Week 16: Stats and Projections vs. 49ers

Jonathan Taylor and the Indianapolis Colts will meet the San Francisco 49ers and their 12th-ranked rushing defense (106.1 yards allowed per game) in Week 16, on Monday at 8:15 p.m. ET.

For more info on Taylor, if you're thinking about him for your DFS lineup, check out this article before his upcoming game against the 49ers.

Thinking about playing Taylor this week? Start building your FanDuel fantasy football lineup today!

Jonathan Taylor Week 16 Fantasy Football Projection

• Matchup: Indianapolis Colts vs. San Francisco 49ers
• Game Date: December 22, 2025
• Game Time: 8:15 p.m.
• Projected Fantasy Points: 17.2
• PPR Projected Fantasy Points: 18.9
• Projected Rushing Yards: 94.54
• Projected Rushing TDs: 0.80
• Projected Receiving Yards: 24.20
• Projected Receiving TDs: 0.12

Projections provided by numberFire

Taylor Fantasy Performance

• Taylor is currently the top fantasy player at his position (third overall), piling up 284.1 fantasy points (20.3 per game).
• Over his last three games, Taylor has totaled 33.6 fantasy points (11.2 per game) as he's rushed for 246 yards and scored one touchdown on 67 attempts. In the passing game, he has contributed 50 yards on six catches (nine targets).
• Taylor has amassed 86.8 fantasy points (17.4 per game) in his last five games, as he's scampered for 548 yards with four touchdowns on 115 attempts. In the passing game, he has contributed 100 yards on 11 receptions (15 targets).
• The highlight of Taylor's fantasy season came against the Atlanta Falcons in Week 10, when he compiled 46.6 fantasy points with 244 rushing yards and three TDs on 32 carries. As a receiver, he reeled in three balls (on three targets) for 42 yards.
• From a fantasy standpoint, Jonathan Taylor's game versus the Pittsburgh Steelers in Week 9 was his worst of the year, as he put up just 5.7 fantasy points. He ran for 45 yards on 14 carries on the day with two catches for 12 yards.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

49ers Defensive Performance

• Three players have registered over 300 yards passing in a game against San Francisco this season.
• A total of 13 players have thrown for at least one TD versus the 49ers this season.
• San Francisco has allowed at least two TD passes to eight opposing QBs this year.
• Three players have thrown for at least three touchdowns in a game against the 49ers this season.
• A total of three players have recorded over 100 yards receiving in a game versus San Francisco this season.
• The 49ers have allowed 24 players to catch a TD pass versus them this year.
• San Francisco has allowed just one player to catch two or more TD passes in a game this season.
• Two players have racked up over 100 yards rushing in a game against the 49ers this year.
• A total of eight players have run for at least one touchdown against San Francisco this year.
• The 49ers have allowed at least two rushing touchdowns to just one player this year.

Want more data and analysis on Jonathan Taylor? Check out FanDuel Research for all the latest and in-depth fantasy and betting coverage.