James Madison vs Louisiana Prediction, Odds, Picks, Best Bets for Week 7 2025

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The James Madison Dukes will face the Louisiana Ragin' Cajuns in college football action on Saturday.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding today's NCAA football betting odds.

James Madison vs Louisiana Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: James Madison: (-1205) | Louisiana: (+750)
Spread: James Madison: -18.5 (-105) | Louisiana: +18.5 (-115)
Total: 45.5 -- Over: (-110) | Under: (-110)

James Madison is 4-1-0 against the spread this year.
As an 18.5-point or greater favorite, James Madison has one win ATS (1-1) this season.
James Madison has had one game (of five) go over the total this year.
Louisiana has posted one win against the spread this season.
Louisiana is winless ATS (0-1) when playing as at least 18.5-point underdogs this year.
Louisiana has seen three of its four games go over the point total.

All college football win probability predictions and picks are according to numberFire.
Prediction: Dukes win (86.6%)

James Madison is favored by 18.5 points (-105 to cover) in this matchup. Louisiana, the underdog, is -115.

A total of 45.5 points has been set for the James Madison-Louisiana game on Oct. 11, with the over available at -110 and the under at -110.

Louisiana is a +750 underdog on the moneyline, while James Madison is a -1205 favorite.

	Point Scored (PG)	Points Scored CFB Rank	Points Allowed (PG)	Points Allowed CFB Rank	Average Total	Total Games
James Madison	27.8	87	13.6	12	52.9	5
Louisiana	28.2	83	32.2	107	48.8	5

Check out even more in-depth James Madison vs. Louisiana analysis on FanDuel Research.

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