James Cook Fantasy Football Week 6: Stats and Projections vs. Falcons

In Week 6 (Monday at 7:15 p.m. ET), running back James Cook and the Buffalo Bills will meet the Atlanta Falcons, who have the 16th-ranked run defense in the NFL (109.0 yards conceded per game).

Daily fantasy players, is Cook worth a look for his upcoming game against the Falcons? See below, because we can help you make the right decision.

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James Cook Week 6 Fantasy Football Projection

• Matchup: Buffalo Bills at Atlanta Falcons
• Game Date: October 13, 2025
• Game Time: 7:15 p.m.
• Projected Fantasy Points: 15.8
• PPR Projected Fantasy Points: 17.0
• Projected Rushing Yards: 89.26
• Projected Rushing TDs: 0.67
• Projected Receiving Yards: 22.86
• Projected Receiving TDs: 0.11

Projections provided by numberFire

Cook Fantasy Performance

• With 83.9 fantasy points in 2025 (16.8 per game), Cook is the sixth-ranked player at the RB position and 26th among all players.
• Looking at his last three games, Cook has totaled 42.2 fantasy points (14.1 per game) as he's rushed for 274 yards and scored two touchdowns on 56 carries. As a receiver, he's chipped in with 28 yards on six grabs (eight targets).
• The peak of Cook's fantasy season came against the New York Jets in Week 2, when he put up 25.5 fantasy points with one reception (on one target) for three yards.
• From a fantasy perspective, James Cook delivered his lowest fantasy-point total of the season (4.9 points) last week against the New England Patriots, rushing for 49 yards on 15 carries.

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Falcons Defensive Performance

• Atlanta has not allowed someone to record more than 300 yards passing in a game this season.
• A total of Two players have thrown for at least one TD versus the Falcons this season.
• Atlanta has allowed at least two passing TDs to two opposing QBs this year.
• The Falcons have allowed one player to throw for at least three TDs in a game this season.
• No player has racked up more than 100 yards receiving in a game against Atlanta this year.
• The Falcons have allowed a touchdown catch by four players this year.
• Atlanta has allowed at least two receiving TDs to one player this season.
• The Falcons have not given up more than 100 yards rushing to an opposing player this year.
• Atlanta has given up at least one rushing TD to two players this season.
• The Falcons have not allowed an opposing player to score two or more rushing TDs versus them this season.

Want more data and analysis on James Cook? Check out FanDuel Research for all the latest and in-depth fantasy and betting coverage.