James Cook Fantasy Football Week 17: Stats and Projections vs. Eagles

Buffalo Bills RB James Cook will be up against the 21st-ranked rushing defense of the Philadelphia Eagles (123.5 yards allowed per game) in Week 17, at 4:25 p.m. ET on Sunday.

With Cook's next game against the Eagles, should you consider him for your daily fantasy lineup? Scroll down for more stats and info.

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James Cook Week 17 Fantasy Football Projection

• Matchup: Buffalo Bills vs. Philadelphia Eagles
• Game Date: December 28, 2025
• Game Time: 4:25 p.m.
• Projected Fantasy Points: 16.5
• PPR Projected Fantasy Points: 17.5
• Projected Rushing Yards: 103.49
• Projected Rushing TDs: 0.71
• Projected Receiving Yards: 17.49
• Projected Receiving TDs: 0.10

Projections provided by numberFire

Cook Fantasy Performance

• At the RB position, Cook has been one of the top players in fantasy, as he ranks fourth in the NFL with 17.3 fantasy points per game (260.0 total points). Overall, he is 15th in fantasy points.
• Over his last three games, Cook has totaled 63.6 fantasy points (21.2 per game) as he's run for 304 yards and scored four touchdowns on 56 attempts. In the receiving game, he has contributed 52 yards on five catches (seven targets) with one TDs.
• Cook has totaled 98.2 fantasy points (19.6 per game) in his last five games, as he's rushed for 564 yards with five touchdowns on 105 attempts. In the passing game, he has contributed 98 yards on 11 receptions (13 targets) with one TDs.
• The highlight of Cook's fantasy season was a Week 8 outburst against the Carolina Panthers, when he tallied 33.6 fantasy points (19 receptions, 216 yards, 2 TDs).
• From a fantasy standpoint, James Cook stumbled to his worst performance of the season in Week 5 against the New England Patriots, running 15 times for 49 yards (4.9 fantasy points).

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Eagles Defensive Performance

• Two players have posted over 300 yards passing in a game against Philadelphia this season.
• The Eagles have allowed 10 players to pass for at least one TD in a game this year.
• Philadelphia has allowed only three players to throw for two or more TDs in a game this year.
• The Eagles have not allowed someone to throw for at least three TDs against them in a game this year.
• A total of seven players have put up more than 100 yards receiving in a game against Philadelphia this season.
• The Eagles have allowed a touchdown catch by 13 players this year.
• No player has caught more than one TD pass versus Philadelphia this season.
• The Eagles have allowed just two players to put up over 100 yards rushing in a game this season.
• Philadelphia has given up at least one rushing TD to 13 players this season.
• Just two players have rushed for more than one TD versus the Eagles this season.

Want more data and analysis on James Cook? Check out FanDuel Research for all the latest and in-depth fantasy and betting coverage.