Islanders vs Sharks NHL Prediction, Odds, Picks, Best Bets for Oct. 21

The Tuesday schedule in the NHL includes a matchup between the New York Islanders and the San Jose Sharks.

Get the latest NHL odds ahead of this game on FanDuel Sportsbook.

Islanders vs Sharks Game Info

• New York Islanders (2-3) vs. San Jose Sharks (0-3-2)
• Date: Tuesday, October 21, 2025
• Time: 7 p.m. ET
• Venue: UBS Arena -- Elmont, New York
• Coverage: ESPN+

Islanders vs Sharks Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Islanders vs Sharks Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Islanders win (58.5%)

Islanders vs Sharks Puck Line

• The Islanders are favored by 1.5 goals (+106 to cover). San Jose, the underdog, is -130.

Islanders vs Sharks Over/Under

• An over/under of 6.5 has been set for Islanders-Sharks on Oct. 21, with the over being -106 and the under -114.

Islanders vs Sharks Moneyline

• San Jose is a +180 underdog on the moneyline, while New York is a -220 favorite at home.

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