Iowa State vs Eastern Illinois College Basketball Prediction, Odds, Picks, Best Bets for Dec. 14

The Eastern Illinois Panthers (2-7) will visit the Iowa State Cyclones (10-0) after losing five road games in a row.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Iowa State vs. Eastern Illinois Game Info and Odds

• Game day: Sunday, December 14, 2025
• Game time: 1 p.m. ET
• TV channel: ESPN+
• Location: Ames, Iowa
• Arena: James H. Hilton Coliseum

Iowa State vs. Eastern Illinois Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Iowa State win (99.6%)

Before you bet on Sunday's Iowa State-Eastern Illinois spread (Iowa State -43.5) or over/under (145.5 points), check out the betting insights and trends below.

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Iowa State vs. Eastern Illinois: ATS Betting Stats and Trends

• Iowa State has covered seven times in 10 matchups with a spread this season.
• Eastern Illinois has won three games against the spread this season, while failing to cover five times.
• Against the spread last year, the Cyclones played worse at home, covering nine times in 17 home games, and seven times in 11 road games.
• The Panthers' winning percentage against the spread at home is .333 (1-2-0). On the road, it is .400 (2-3-0).

Iowa State vs. Eastern Illinois Head-to-Head Comparison

• With 80.3 points scored per game and 68.3 points allowed last year, Iowa State was 34th in the country offensively and 61st defensively.
• Iowa State grabbed 32.7 rebounds per game and conceded 28.3 boards last year, ranking 142nd and 31st, respectively, in the country.
• Last season Iowa State was ranked 77th in college basketball in assists with 15 per game.
• Iowa State was 232nd in college basketball in turnovers per game (11.6) and 13th-best in turnovers forced (14.4) last season.
• Eastern Illinois put up only 66.5 points per game (18th-worst in college basketball) last year, but it played better on defense, where it gave up 69 points per game (81st-ranked).
• Eastern Illinois averaged 31.3 rebounds per game (214th-ranked in college basketball). It ceded 33.2 rebounds per contest (300th-ranked).
• Last year Eastern Illinois ranked 330th in college basketball in assists, averaging 11.3 per game.
• With 14.2 forced turnovers per game, Eastern Illinois was 17th-best in college basketball. It ranked 232nd in college basketball by averaging 11.6 turnovers per contest.

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