Iowa State vs BYU Prediction, Odds, Picks, Best Bets for Week 9 2025

NCAA football action on Saturday includes the Iowa State Cyclones facing the BYU Cougars.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Iowa State vs BYU Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Iowa State: (-146) | BYU: (+124)
• Spread: Iowa State: -2.5 (-124) | BYU: +2.5 (102)
• Total: 49.5 -- Over: (-102) | Under: (-120)

Iowa State vs BYU Betting Trends

• Iowa State's record against the spread is 3-4-0.
• Iowa State has two wins ATS (2-3) as a 2.5-point or higher favorite in 2025.
• Iowa State has played seven games this year, and three of them have gone over the total.
• BYU has five wins in seven contests against the spread this season.
• BYU has covered every time (1-0) as a 2.5-point or greater underdog this year.
• BYU has seen three of its seven games hit the over.

Iowa State vs BYU Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Cougars win (61.5%)

Iowa State vs BYU Point Spread

BYU is the underdog by 2.5 points against Iowa State. BYU is -124 to cover the spread, and Iowa State is +102.

Iowa State vs BYU Over/Under

The Iowa State-BYU matchup on Oct. 25 has been given an over/under of 49.5 points. The over is -102 and the under is -120.

Iowa State vs BYU Moneyline

BYU is a +124 underdog on the moneyline, while Iowa State is a -146 favorite.

Iowa State vs. BYU Points Insights

Iowa State vs. BYU Game Info

• Game day: Saturday, October 25, 2025
• Game time: 3:30 p.m. ET
• TV channel: FOX
• Location: Ames, Iowa
• Stadium: Jack Trice Stadium

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