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Indiana vs Purdue Prediction, Odds, Picks, Best Bets for Week 14 2025

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Indiana vs Purdue Prediction, Odds, Picks, Best Bets for Week 14 2025

Friday's slate in college football includes a matchup between the Indiana Hoosiers and the Purdue Boilermakers.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

Indiana vs Purdue Odds & Spread

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  • All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
  • Moneyline: Indiana: (-10000) | Purdue: (+2400)
  • Spread: Indiana: -28.5 (-110) | Purdue: +28.5 (-110)
  • Total: 54.5 -- Over: (-110) | Under: (-110)

Indiana vs Purdue Betting Trends

  • Against the spread, Indiana is 6-5-0 this year.
  • Indiana has two wins ATS (2-1) as a 28.5-point or higher favorite in 2025.
  • Indiana has played 11 games this year, and seven of them have gone over the total.
  • Against the spread, Purdue is 5-6-0 this year.
  • Purdue is unbeaten ATS (1-0) as a 28.5-point underdog or more this year.
  • Purdue has seen three of its 11 games go over the point total.

Indiana vs Purdue Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Hoosiers win (98%)

Indiana vs Purdue Point Spread

Purdue is the underdog by 28.5 points against Indiana. Purdue is -110 to cover the spread, and Indiana is -110.

Indiana vs Purdue Over/Under

Indiana versus Purdue on Nov. 28 has an over/under of 54.5 points, with the over -110 and the under -110.

Indiana vs Purdue Moneyline

Indiana is the favorite, -10000 on the moneyline, while Purdue is a +2400 underdog.

Indiana vs. Purdue Points Insights

Point Scored (PG)
Points Scored CFB Rank
Points Allowed (PG)
Points Allowed CFB Rank
Average Total
Total Games
Indiana43.3211.6251.111
Purdue20.211929.610252.011

Indiana vs. Purdue Game Info

  • Game day: Friday, November 28, 2025
  • Game time: 7:30 p.m. ET
  • TV channel: NBC
  • Location: West Lafayette, Indiana
  • Stadium: Ross-Ade Stadium

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Check out even more in-depth Indiana vs. Purdue analysis on FanDuel Research.

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