Indiana vs Penn State Prediction, Odds, Picks, Best Bets for Week 11 2025

The Indiana Hoosiers are among the college football squads in action on Saturday, versus the Penn State Nittany Lions.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Indiana vs Penn State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Indiana: (-671) | Penn State: (+490)
• Spread: Indiana: -14.5 (-105) | Penn State: +14.5 (-115)
• Total: 49.5 -- Over: (-110) | Under: (-110)

Indiana vs Penn State Betting Trends

• Indiana's record against the spread is 6-3-0.
• Indiana's ATS record as 14.5-point or bigger favorites is 4-2.
• There have been six Indiana games (of nine) that hit the over this season.
• Penn State has but one win versus the spread this season.
• Penn State has no wins ATS (0-1) as a 14.5-point underdog or greater this year.
• This season, six of Penn State's eight games have gone over the point total.

Indiana vs Penn State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Hoosiers win (89.4%)

Indiana vs Penn State Point Spread

Indiana is a 14.5-point favorite against Penn State. Indiana is -105 to cover the spread, and Penn State is -115.

Indiana vs Penn State Over/Under

Indiana versus Penn State, on Nov. 8, has an over/under of 49.5, with the over being -110 and the under -110.

Indiana vs Penn State Moneyline

Indiana is the favorite, -671 on the moneyline, while Penn State is a +490 underdog.

Indiana vs. Penn State Points Insights

Indiana vs. Penn State Game Info

• Game day: Saturday, November 8, 2025
• Game time: 12 p.m. ET
• TV channel: FOX
• Location: University Park, Pennsylvania
• Stadium: West Shore Home Field at Beaver Stadium

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