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Indiana vs Michigan State Prediction, Odds, Picks, Best Bets for Week 8 2025

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Indiana vs Michigan State Prediction, Odds, Picks, Best Bets for Week 8 2025

In college football action on Saturday, the Indiana Hoosiers face the Michigan State Spartans.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Indiana vs Michigan State Odds & Spread

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  • All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
  • Moneyline: Indiana: (-7692) | Michigan State: (+2200)
  • Spread: Indiana: -27.5 (-114) | Michigan State: +27.5 (-106)
  • Total: 49.5 -- Over: (-110) | Under: (-110)

Indiana vs Michigan State Betting Trends

  • Indiana is 4-2-0 against the spread this year.
  • Indiana is unbeaten ATS (2-0) as a 27.5-point favorite or greater this year.
  • This season, three of Indiana's six games have gone over the point total.
  • Michigan State owns two wins against the spread this year.
  • Michigan State has seen four of its six games hit the over.

Indiana vs Michigan State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Hoosiers win (97.2%)

Indiana vs Michigan State Point Spread

Michigan State is an underdog by 27.5 points against Indiana. Michigan State is -106 to cover the spread, and Indiana is -114.

Indiana vs Michigan State Over/Under

A total of 49.5 points has been set for the Indiana-Michigan State game on Oct. 18, with the over available at -110 and the under at -110.

Indiana vs Michigan State Moneyline

Michigan State is a +2200 underdog on the moneyline, while Indiana is a -7692 favorite.

Indiana vs. Michigan State Points Insights

Point Scored (PG)
Points Scored CFB Rank
Points Allowed (PG)
Points Allowed CFB Rank
Average Total
Total Games
Indiana44.8411.3452.76
Michigan State29.56531.811651.06

Indiana vs. Michigan State Game Info

  • Game day: Saturday, October 18, 2025
  • Game time: 3:30 p.m. ET
  • TV channel: Peacock
  • Location: Bloomington, Indiana
  • Stadium: Memorial Stadium (Bloomington, IN)

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Check out even more in-depth Indiana vs. Michigan State analysis on FanDuel Research.

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