Illinois vs USC College Basketball Prediction, Odds, Picks, Best Bets for Feb. 18

Big Ten action features the No. 10 Illinois Fighting Illini (21-5, 12-3 Big Ten) on the road against the USC Trojans (18-7, 7-7 Big Ten) on Wednesday, February 18, 2026 at 10 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Illinois vs. USC Game Info and Odds

• Game day: Wednesday, February 18, 2026
• Game time: 10 p.m. ET
• TV channel: Big Ten Network
• Location: Los Angeles, California
• Arena: Galen Center

See the betting insights and trends below before making a wager on Wednesday's Illinois-USC spread (Illinois -9.5) or over/under (150.5 points).

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Illinois vs. USC: ATS Betting Stats and Trends

• Illinois has won 16 games against the spread this season, while failing to cover 10 times.
• USC has covered 13 times in 24 chances against the spread this season.
• Illinois covers the spread when it is a 9.5-point favorite or more 58.8% of the time. That's more often than USC covers as an underdog of 9.5 or more (33.3%).
• The Fighting Illini have a worse record against the spread when playing at home (9-6-0) than they do in road games (5-2-0).
• The Trojans have been better against the spread on the road (5-4-0) than at home (6-5-0) this year.
• Against the spread, in conference action, Illinois is 9-6-0 this season.
• USC's Big Ten record against the spread is 8-6-0.

Illinois vs. USC: Moneyline Betting Stats

• Illinois has won in 14, or 82.4%, of the 17 contests it has been named as the moneyline favorite in this year.
• This season, the Fighting Illini have been victorious 11 times in 13 chances when named as a favorite of at least -481 or better on the moneyline.
• USC is 3-5 in games it was listed as the moneyline underdog (winning 37.5% of those games).
• The Trojans have played in three games as a moneyline underdog with odds of +360 or longer without claiming a victory.
• Illinois has an implied victory probability of 82.8% according to the moneyline set by sportsbooks for this matchup.

Illinois vs. USC Head-to-Head Comparison

• Illinois was the ninth-best team in the country in points scored (83.6 per game) and 263rd in points allowed (74.8) last year.
• Last year, Illinois was best in the country in rebounds (39.7 per game) and 104th in rebounds conceded (30.1).
• Illinois was 83rd in the nation in assists (14.9 per game) last year.
• Last season, Illinois was 215th in college basketball in turnovers committed (11.4 per game) and second-worst in turnovers forced (8.5).
• With 76.7 points per game on offense, USC was 96th in college basketball last season. On defense, it ceded 74.6 points per contest, which ranked 255th in college basketball.
• USC averaged 29.2 rebounds per game (325th-ranked in college basketball) last year, while allowing 29.1 rebounds per contest (56th-ranked).
• USC put up 15.5 dimes per game, which ranked them 59th in the country.
• USC committed 11.8 turnovers per game (246th-ranked in college basketball). It forced 11.9 turnovers per contest (121st-ranked).

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!