Illinois vs Pennsylvania College Basketball Prediction, Odds, Picks, Best Bets for Nov. 5

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The Pennsylvania Quakers (0-0) go up against the Illinois Fighting Illini (1-0) at State Farm Center on November 5, 2026.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Illinois vs. Pennsylvania Game Info and Odds

Take a look at some betting insights for Illinois (-30.5) versus Pennsylvania on Thursday. The over/under is set at 168.5 points for this game.

Illinois went 22-15-0 ATS last season.
Pennsylvania went 19-10-0 ATS last year.
The Fighting Illini did a better job covering the spread when playing on the road (6-4-0) than they did in home games (10-7-0) last year.
Last year, the Quakers were 8-5-0 at home against the spread (.615 winning percentage). On the road, they were 9-3-0 ATS (.750).

Illinois was 28th in the nation in points scored (83.2 per game) and 51st in points allowed (68.8) last season.
Last season, Illinois was sixth-best in college basketball in rebounds (37.8 per game) and 17th-best in rebounds conceded (27.6).
Last season Illinois was ranked 143rd in the nation in assists with 14.2 per game.
In terms of turnovers, Illinois was seventh-best in college basketball in committing them (8.5 per game) last season. However, it was -6-worst in forcing them (7.2 per game).
With 75.9 points per game on offense, Pennsylvania was 173rd in the country last year. At the other end of the court, it ceded 74.4 points per contest, which ranked 194th in college basketball.
Last year Pennsylvania pulled down 32.3 rebounds per game (152nd-ranked in college basketball) and ceded 33.1 rebounds per contest (302nd-ranked).
Last year Pennsylvania ranked 165th in college basketball in assists, delivering 13.9 per game.
With 10.3 turnovers per game, Pennsylvania ranked 115th in the country. It forced 11.4 turnovers per contest, which ranked 141st in college basketball.

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