Houston vs Oklahoma State Prediction, Odds, Picks, Best Bets for Week 7 2025

The Houston Cougars will take on the Oklahoma State Cowboys in college football action on Saturday.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Houston vs Oklahoma State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Houston: (-699) | Oklahoma State: (+500)
• Spread: Houston: -15.5 (-112) | Oklahoma State: +15.5 (-108)
• Total: 47.5 -- Over: (-115) | Under: (-105)

Houston vs Oklahoma State Betting Trends

• Against the spread, Houston is 3-2-0 this year.
• Houston has yet to lose ATS (1-0) as a 15.5-point favorite or greater this season.
• There have been three Houston games (of five) that hit the over this season.
• Oklahoma State has but one win versus the spread this year.
• Oklahoma State has won once ATS (1-2) as a 15.5-point underdog or greater this season.
• A pair of Oklahoma State five games in 2025 have gone over the point total.

Houston vs Oklahoma State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Cougars win (85.5%)

Houston vs Oklahoma State Point Spread

Oklahoma State is an underdog by 15.5 points versus Houston. Oklahoma State is -108 to cover the spread, and Houston is -112.

Houston vs Oklahoma State Over/Under

Houston versus Oklahoma State on Oct. 11 has an over/under of 47.5 points, with the over -115 and the under -105.

Houston vs Oklahoma State Moneyline

Looking at the moneyline for Houston-Oklahoma State, Houston is the favorite at -699, and Oklahoma State is +500.

Houston vs. Oklahoma State Points Insights

Houston vs. Oklahoma State Game Info

• Game day: Saturday, October 11, 2025
• Game time: 12 p.m. ET
• TV channel: TNT
• Location: Stillwater, Oklahoma
• Stadium: Boone Pickens Stadium

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Check out even more in-depth Houston vs. Oklahoma State analysis on FanDuel Research.