Guardians vs Tigers Prediction, Odds, Moneyline, Spread & Over/Under for AL Wild Card Game 2 on Oct. 1

Odds updated as of 9:11 p.m.

The Wednesday slate in the MLB includes a matchup between the Cleveland Guardians and the Detroit Tigers in Game 2 of the AL Wild Card Series.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Tigers Game Info

• Cleveland Guardians (88-74) vs. Detroit Tigers (87-75)
• Date: Wednesday, October 1, 2025
• Time: 1:08 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: ESPN Networks

Guardians vs Tigers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-120) | DET: (+102)
• Spread: CLE: +1.5 (-215) | DET: -1.5 (+176)
• Total: 6.5 -- Over: (-118) | Under: (-104)

Guardians vs Tigers Probable Starting Pitchers

Probable Pitchers: Tanner Bibee (Guardians) - 12-11, 4.24 ERA vs Casey Mize (Tigers) - 14-6, 3.87 ERA

The probable pitchers are Tanner Bibee (12-11, 4.24 ERA) for the Guardians and Casey Mize (14-6, 3.87 ERA) for the Tigers. When Bibee starts, his team is 18-11-0 against the spread this season. Bibee's team has a record of 10-5 this season when he starts and they are the favorite on the moneyline. The Tigers have a 16-11-0 ATS record in Mize's 27 starts with a set spread. The Tigers have a 5-3 record in Mize's eight starts this season when they were the underdog on the moneyline.

Guardians vs Tigers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (51.5%)

Guardians vs Tigers Moneyline

• Cleveland is the favorite, -120 on the moneyline, while Detroit is a +102 underdog on the road.

Guardians vs Tigers Spread

• The Tigers are 1.5-run favorites against the spread for this matchup with the Guardians. The Tigers are +176 to cover, while the Guardians are -215 to cover as a 1.5-run underdog on the runline.

Guardians vs Tigers Over/Under

• The over/under for the Guardians versus Tigers game on Oct. 1 has been set at 6.5, with -118 odds on the over and -104 odds on the under.

Bet on Cleveland Guardians vs. Detroit Tigers on FanDuel today!

Guardians vs Tigers Betting Trends

• The Guardians have come away with 44 wins in the 69 contests they have been listed as the favorites in this season.
• This year Cleveland has won 34 of 51 games when listed as at least -120 on the moneyline.
• The Guardians' games have gone over the total in 68 of their 159 opportunities.
• The Guardians are 86-73-0 against the spread in their 159 games with a line set by sportsbooks this season.
• The Tigers have compiled a 22-22 record in games they were listed as the moneyline underdog (winning 50% of those games).
• Detroit is 10-16 (winning only 38.5% of its games) when playing as a moneyline underdog of +102 or longer.
• The Tigers have combined with opponents to hit the over on the total 78 times this season for a 78-72-6 record against the over/under.
• The Tigers have put together a 71-85-0 record against the spread this season (covering 45.5% of the time).

Guardians Player Leaders

• Jose Ramirez has 168 hits and an OBP of .360, both of which lead Cleveland hitters this season. He has a .283 batting average and a slugging percentage of .503.
• He is 21st in batting average, 19th in on-base percentage, and 16th in slugging among qualifying hitters in MLB.
• Ramirez has hit safely in three games in a row. In his last five games he is hitting .278 with a double, three walks and an RBI.
• Steven Kwan has hit 11 homers this season while driving in 56 runs. He's batting .272 this season and slugging .374 with an on-base percentage of .330.
• He ranks 36th in batting average, 72nd in on-base percentage and 129th in slugging in the major leagues.
• Kyle Manzardo is batting .234 with a .455 slugging percentage and 70 RBI this year.
• Manzardo has recorded a hit in four games in a row. During his last five outings he is hitting .235 with a double, a home run and two RBIs.
• Angel Martinez has been key for Cleveland with 100 hits, an OBP of .269 plus a slugging percentage of .359.
• Martinez has safely hit in two straight games. During his last five outings he is batting .188 with a walk.

Tigers Player Leaders

• Gleyber Torres a has .358 on-base percentage to lead the Tigers. He's batting .256 while slugging .387.
• Including all qualified players in the big leagues, he is 77th in batting average, 23rd in on-base percentage and 118th in slugging percentage.
• Riley Greene's 155 hits and .493 slugging percentage both pace his team. He has a batting average of .258 with an on-base percentage of .313.
• He is currently 69th in batting average, 104th in on-base percentage and 21st in slugging percentage among all qualifying hitters.
• Spencer Torkelson has 27 doubles, a triple, 31 home runs and 72 walks while batting .240.
• Zach McKinstry has 23 doubles, 11 triples, 12 home runs and 46 walks while batting .259.

Guardians vs Tigers Head to Head

• 9/30/2025: 2-1 DET (Favorite: Tigers, Spread: -1.5, Total: 6, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 9/25/2025: 4-2 DET (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 9/23/2025: 5-2 CLE (Favorite: Tigers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 9/18/2025: 3-1 CLE (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/17/2025: 4-0 CLE (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/16/2025: 7-5 CLE (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/6/2025: 7-2 DET (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 7/5/2025: 1-0 DET (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/4/2025: 2-1 DET (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/25/2025: 5-0 DET (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -290, Underdog Moneyline: +235)

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