Guardians vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 19

Odds updated as of 6:12 p.m.

The Cleveland Guardians will face the San Francisco Giants in MLB action on Wednesday.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Guardians vs Giants Game Info

• Cleveland Guardians (61-65) vs. San Francisco Giants (51-74)
• Date: Wednesday, August 19, 2026
• Time: 6:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and NBCS-BA

Guardians vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-215) | SF: (+198)
• Spread: CLE: -1.5 (-105) | SF: +1.5 (-114)
• Total: 7.5 -- Over: (+102) | Under: (-124)

Guardians vs Giants Probable Starting Pitchers

Probable Pitchers: Parker Messick (Guardians) - 9-7, 2.59 ERA vs Matt Wilkinson (Giants) - 0-0, 0.00 ERA

The Guardians will give the ball to Parker Messick (9-7, 2.59 ERA), who is eyeing win No. 10 on the season, and the Giants will counter with Matt Wilkinson. Messick's team is 12-12-0 against the spread in his starts this season. Messick's team has a record of 8-10 this season when he starts and they are the favorite on the moneyline. Wilkinson never pitched as a moneyline underdog a season ago.

Guardians vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (63.4%)

Guardians vs Giants Moneyline

• San Francisco is a +198 underdog on the moneyline, while Cleveland is a -215 favorite at home.

Guardians vs Giants Spread

• The Guardians are hosting the Giants and are favored by 1.5 runs on the spread. The Guardians are -105 to cover the runline, with the Giants being -114.

Guardians vs Giants Over/Under

• The over/under for the Guardians versus Giants game on Aug. 19 has been set at 7.5, with +102 odds on the over and -124 odds on the under.

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Guardians vs Giants Betting Trends

• The Guardians have won in 32, or 47.1%, of the 68 contests they have been named as odds-on favorites in this year.
• These are the best odds of a victory sportsbooks have given Cleveland this season, with a -215 moneyline set for this game.
• The Guardians and their opponents have gone over in 59 of their 120 games with a total set by sportsbooks this season.
• The Guardians are 57-63-0 against the spread in their 120 games with a line set by sportsbooks this season.
• The Giants have been the moneyline underdog 78 total times this season. They've gone 27-51 in those games.
• San Francisco has a record of 1-2 in games it has played as a moneyline underdog with odds of +198 or longer (33.3%).
• The Giants have played in 122 games with a set over/under, and have combined with their opponents to go over the total 57 times (57-56-9).
• The Giants have a 55-67-0 record ATS this season (covering 45.1% of the time).

Guardians Player Leaders

• Chase DeLauter leads Cleveland in slugging percentage (.442) and total hits (115) this season. He's batting .285 with an on-base percentage of .358.
• Among qualified hitters in baseball, he ranks 20th in batting average, 36th in on-base percentage, and 55th in slugging.
• Jose Ramirez has 20 doubles, 10 home runs and 54 walks. He's batting .241 and slugging .388 with an on-base percentage of .344.
• His batting average is 100th among qualified players, his on-base percentage 54th, and his slugging percentage 108th.
• Ramirez enters this game looking to extend his three-game hit streak. During his last five outings he is hitting .375 with two doubles, four walks and an RBI.
• Steven Kwan has 107 hits this season and a team-best OBP of .369.
• Brayan Rocchio has 10 home runs, 51 RBI and a batting average of .253 this season.

Giants Player Leaders

• Jung Hoo Lee has a team-best OBP (.328) and slugging percentage (.432). He's batting .292.
• Including all qualifying hitters in the majors, he ranks 13th in batting average, 78th in on-base percentage and 66th in slugging percentage.
• Rafael Devers has 30 doubles, a triple, 25 home runs and 52 walks while hitting .244. He's slugging .470 with an on-base percentage of .318.
• He ranks 94th in batting average, 95th in on-base percentage and 33rd in slugging percentage in MLB.
• Willy Adames has 25 doubles, a triple, 19 home runs and 36 walks while batting .224.
• Bryce Eldridge has 15 doubles, 14 home runs and 42 walks while batting .250.

Guardians vs Giants Head to Head

• 8/18/2026: 8-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +176)
• 6/19/2025: 2-1 SF (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 6/18/2025: 4-2 CLE (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/17/2025: 3-2 CLE (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/7/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/6/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/5/2024: 4-2 SF (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 9/13/2023: 6-5 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/12/2023: 3-1 CLE (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 9/11/2023: 5-4 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

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